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《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:

20

期数:

2019年04期

页码:

508-510

栏目:

论　著

出版日期:

2019-05-16

文章信息/Info

Title:

Clinical characteristics and risk factors of multiple falls in elderly patients with Parkinson's disease

作者:

焦信忠

茌平县人民医院神经内科，山东 聊城 252100

Author(s):

JIAOXin-zhong

Departmentof Neurology, ChipingCountyPeople's Hospital,Liaocheng,Shandong252100,China

关键词:

帕金森病; 老年人; 多次跌倒; 临床特点; 危险因素

Keywords:

Parkinson's disease;  Elderly;  Multiple falls;  Clinical characteristics;  Risk factors

分类号:

R742.5

DOI:

-

摘要:

目的 探讨老年帕金森病患者多次跌倒的临床特点，并分析出现该症状的相关危险因素。方法 回顾性 分析2015年3月—2018年4月茌平县人民医院收治的129例老年帕金森病患者的临床资料，依据患者1年内有无 跌倒分为对照组（无跌倒，87例）与观察组（跌倒次数≥1次，42例），分析两组临床特点，并进行危险因素分 析。结果 两组年龄、起病年龄、简易精神状态评价量表（MMSE）评分、老年抑郁量表（GDS-15）评分、 医院焦虑和抑郁量表（HADS）评分对比，差异无统计学意义（P>0.05）；观察组日常生活能力评分量表 （SEADL）评分低于对照组，爱泼沃斯嗜睡量表（ESS）评分高于对照组，差异有统计学意义（P<0.05）；两组 性别、失眠情况、病程、是否存在家族史、服药情况对比，差异无统计学意义（P>0.05）；观察组已婚率低于对 照组，同时使用≥3种抗帕金森药物率高于对照组，差异有统计学意义（P<0.05）。经Logistic多因素分析显示， 离异、丧偶或未婚、日常生活能力低、同时使用≥3种抗帕金森药物为导致帕金森患者多次跌倒的危险因素 （OR>1，均P<0.05）。结论 日常生活能力低、同时使用≥3种抗帕金森药物等为导致帕金森患者多次跌倒的危 险因素，临床应尽量控制多种帕金森药物使用情况，以避免或减少多次跌倒现象的发生。

Abstract:

Objective To investigate the clinical features of multiple falls in elderly patients with Par-kinson's disease and to analyze the risk factors. Methods The clinical data of129 elderly patients with Parkinson's disease treated in Chiping County People's Hospital from March2015 to April 2018 were retrospectively analyzed. There were87 cases without falling downin control group, and there were42 cases in observation group（fall times≥1）. The clinical characteristics of the two groups were analyzed, and the risk factors were analyzed. Results There was no significant difference in age, on-set age, simple mental state evaluation scale（MMSE）, Chinese Geriatric Depression scale（GDS-15）,hospital anxiety and depression scale（HADS）score between the two groups（all P>0.05）. Ac-tivity of daily living rating scale（SEADL）score of the observation group was lower than that of the control group, and Epworth sleepiness scale（ESS）score of the observation group was higher than that of the control group（P<0.05）. There was no significant difference in sex, insomnia, course of disease, family history and medication between the two groups（P>0.05）. The married rate of the ob-servation group was lower than that of the control group, and the rate of using more than 3 kinds of anti-Parkinson drugs was higher than that of the control group（P<0.05）. Logistic multivariate analy-sis showed that divorce, widowhood or unmarried, low ability of daily living, and more than 3 kinds of anti-Parkinson drugs were the risk factors of multiple falls in patients with Parkinson's disease（OR>1, P<0.05）. Conclusion Low daily living ability and use of more than3 kinds of anti-Parkinson drugs are the risk factors of multiple falls in patients with Parkinson's disease. The clinical use of mul-tiple Parkinson's drugs should be controlled as far as possible to avoid or reduce the occurrence of mul-tiple falls.

参考文献/References:

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备注/Memo

备注/Memo:

作者简介：焦信忠，本科，主治医师。研究方向：脑血管病，帕金森病，痴呆，神经精神障碍等 通信作者：焦信忠，E-mail：jsy135246985112@163.com

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更新日期/Last Update: 2019-04-28