|本期目录/Table of Contents|

[1]张俏,潘殿柱.经支气管镜确诊肺癌患者的临床特征分析[J].慢性病学杂志,2020,21(09):1291-1293.
 ZHANGQiao *,PANDian-zhu.Analysis of clinical features in patients with lung cancer diagnosed by bronchoscope[J].,2020,21(09):1291-1293.
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经支气管镜确诊肺癌患者的临床特征分析

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
21
期数:
2020年09期
页码:
1291-1293
栏目:
论 著
出版日期:
2020-09-28

文章信息/Info

Title:
Analysis of clinical features in patients with lung cancer diagnosed by bronchoscope
作者:
张俏1潘殿柱2
1.锦州医科大学研究生学院,辽宁 锦州 121000; 2.锦州医科大学附属第一医院,辽宁 锦州 121000
Author(s):
ZHANGQiao * PANDian-zhu
*Graduate School, JinzhouMedicalUniversity,Jinzhou,Liaoning121000,China Correspondingauthor:PAN Dian-zhu,E-mail:pandianzhu@163.com
关键词:
支气管镜肺癌病理类型临床特征
Keywords:
Bronchoscope Lung cancer Pathological type Clinical features
分类号:
R734.2
DOI:
-
摘要:
目的 探讨经支气管镜确诊肺癌患者的临床特征。方法 收集2016年1月—2019年6月于锦州医科大学 附属第一医院门诊/住院的450例肺癌患者的临床资料,观察并分析病理类型与支气管镜镜下表现及临床特征的关 系。结果 本组肺癌患者以男性为主,发病高峰年龄为51~70岁。经支气管镜确诊肺癌患者的病理类型以鳞癌 多见(44.00%),其次为小细胞肺癌(30.44%)。不同性别组患者的病理类型总体分布差异有统计学意义(χ 2 = 29.46,P<0.01);不同发病部位肺癌的病理类型总体分布差异无统计学意义(P>0.05)。多种方式联合取材的阳 性率(100.00%)均高于钳检(82.44%)、刷检(61.11%)、灌洗(48.44%)等单一方式,差异有统计学意义(P< 0.05)。鳞癌组与小细胞癌组、鳞癌组与腺癌组、腺癌与小细胞癌组比较,其支气管镜下表现分布差异均有统计学 意义(P<0.01)。结论 支气管镜是诊断肺癌的重要方法,肺癌的病理类型与镜下表现及临床特征密切相关。
Abstract:
Objective To observe the clinical features of patients with lung cancer diagnosed by bron-choscope. Method The clinical data of450 cases of lung cancer patients diagnosed atoutpatient / in-patient in the First Affiliated Hospital of Jinzhou Medical University between January 2016 and June 2019 were collected. The relationship between pathological type and clinical features were observed and analyzed. Result Male patients were far more than female patients in this lung carcer group, and the age with highest incident rate was 51-70 years old. The most common pathological type was squa-mous cell carcinoma(44.00%), followed by small cell lung cancer(30.44%). There was a significant difference in pathological types between different genders(χ 2 =29.46, P<0.01). There was no significant difference in pathological types among different locations of lesion(P>0.05). The positive incidence of united biopsy methods(100.00%)was higher than those of single approach such as forceps inspection (82.44%), brush inspection(61.11%)and lavage(48.44%), the differences were statistically significant (P<0.05). In comparisons between two groups, squamous cancer group and small cell cancer group, squamous cancer group and adenocarcinoma group as well as the adenocarcinoma group and small cell cancer group, the differences in bronchoscopy wereall statistically significant(P<0.01). Conclusion Bronchoscope is a critical method in the diagnosis of lung cancer. The pathological types of lung can-cer closely related with the bronchoscopic manifestations and clinical features.

参考文献/References:

[1] Chen W, Zheng R, Zeng H, et al. The incidence and mortality of major cancers in China [J]. Chin J Cancer, 2016,35(1):73. [2] Blandin S, Crosbie A, Balata H,et al.Progress and pros-pects of early detection in lung cancer [J]. Open Biol, 2017,7(9):170-175. [3] 李为民,赵爽,刘伦旭.肺癌早期诊断方法及临床意义[J].四川大 学学报:医学版,2017,48(3):331-335. [4] Chen W, Sun K, Zheng R, et al. Cancer incidence and mortality in China [J]. Cancer Lett,2018,30(1):1-12. [5] 赵焕,郭会芹,张传欣,等.纤维支气管镜下刷取标本液基细胞学 检查在肺癌临床诊断中的价值[J].中华肿瘤杂志,2015,37(6): 431-435. [6] 王艺,陈旭昕,徐剑铖,等.129例肺癌患者病理类型与支气管镜下 表现及临床特征的关系分析[J].中国肺部疾病杂志(电子版), 2018,11(2):190-194. [7] 韩仁强,郑荣寿,张思维,等.1989年—2008年中国肺癌发病性 别、城乡差异及平均年龄趋势分析[J].中国肺癌杂志,2013,16 (9):445-451.[8] 林科雄,钱桂生.纤维支气管镜在肺部疾病诊断和治疗中的价值 [J].中华肺部疾病杂志(电子版),2014,7(4):1-3. [9] Friboulet L, Li N, Katayama R,et al. The ALK inhibitor ceritinib overcomes crizotinib resistance in non- small cell lung cancer [J]. Cancer discov, 2014,4(6):662-673. [10] Bungay HK, Pal CR, DaVies CW,et al.An evaluation of computed tomorgraphy as an aid to diagnosis in patients undergoing bronchoscopy for suspected bronchial carcinoma [J]. Clin Radiol, 2000,55(5):554-560. [11] 钟巍,王孟昭,陈勇,等.支气管镜在肺癌诊断中的应用[J].癌症进 展杂志,2009,7(3):308-313. [12] Bauman JE, Eaton KD, Wallace SG, et al.A phaseⅡ study of pulse dose imatinib mesylate and weekly paclitax-el in patients aged 70 and over with advanced non-small cell lung cancer [J]. BMC Cancer, 2012,12(1):449. [13] 张丽丽.经电子支气管镜不同取材方法对中央型肺癌的诊断价值 [J].医药前沿,2017,7(23):147-148. [14] 聂华萍,梁伟军,刘胜岗,等.158例青年肺癌患者支气管镜下特征 及临床特点分析[J].肿瘤药学,2016(3):212-216. [15] 赵丽娟,朱辉,王可,等.2670例肺癌支气管镜下表现与病理类型 的关系分析[J].中国呼吸与危重症监护杂志,2009,8(3):287-289.

备注/Memo

备注/Memo:
作者简介:张俏,硕士研究生,住院医师,研究方向:内科学(呼吸病学) 通信作者:潘殿柱,E-mail: pandianzhu@163.com
更新日期/Last Update: 2020-09-28