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《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:

21

期数:

2020年07期

页码:

977-980

栏目:

论　著

出版日期:

2020-07-28

文章信息/Info

Title:

Analysis of the influencing factors of quality of life in patients with angioimmunoblastic T-cell lymphoma

作者:

闫春梅1; 白忠旭2

1.中国人民解放军联勤保障部队第988医院血液肿瘤科，郑州 450007； 2.郑州市第二人民医院骨科创伤外科，郑州 450006

Author(s):

YANChun-mei * ; BAIZhong-xu

*Hematology-Oncology Department,The988HospitalofChinese PLA,Zhengzhou450007,China Correspondingauthor: YAN Chun-mei,E-mail:65970162@qq.com

关键词:

血管免疫母细胞性T细胞淋巴瘤; 生存质量; 影响因素

Keywords:

Angioimmunoblastic T-cell lymphoma;  Quality of life;  Influencing factors

分类号:

R733.4

DOI:

-

摘要:

目的 探讨血管免疫母细胞性T细胞淋巴瘤（AITL）患者生存质量状态，分析其相关影响因素。方法 选取182例AITL患者作为研究对象，采用SF-36量表进行问卷调查，对患者生存质量进行评分，将生存质量总 分≥72分定义为生存质量好，<72分为生存质量差，并收集患者相关资料，筛选出AITL患者生存质量的影响因 素。结果 患者治疗前生存质量总平均分为（69.32±6.82）分，治疗后总平均分为（101.62±8.65）分。生存质 量好组与生存质量差组在文化程度、疾病认知度、家庭收入、疾病复发、婚姻状况、居住情况、淋巴结肿大、贫 血和乳酸脱氢酶方面差异有统计学意义（P<0.05）。多因素logistic回归分析结果显示，文化程度（β=2.225， OR=10.596，95%CI 6.363~29.853）、疾病认知度（β=0.992，OR=3.103，95%CI 1.256~9.285）、家庭收入 （β=2.832，OR=12.696，95%CI 4.663~32.593）、疾 病 复 发（β=3.256，OR=15.526，95%CI 3.925~ 28.533）、婚姻情况（β=2.069，OR=18.516，95%CI 4.355~30.563）、居住情况（β=2.005，OR=13.821，95% CI 4.189~33.253）、淋巴结肿大（β=1.325，OR=10.031，95%CI 2.133~22.683）和乳酸脱氢酶（β=6.358， OR=11.852，95%CI 5.278~26.360）是AITL患者生存质量的影响因素（P<0.05）。结论 AITL患者生存质 量相对较差，文化程度、疾病认知度、经济收入、疾病复发、婚姻状况、居住情况、淋巴结肿大和乳酸脱氢酶升 高对患者的生存质量影响较大。

Abstract:

Objective To measure and assess the quality of life in patients with angioimmunoblastic T-cell lymphoma（AITL）, and analyze its related influencing factors. Method Totally182 patients with AITL were selected as the research objects. The patients were divided into two groups according to their quality of life measured by SF-36: SF-36≥72 group and SF-36<72 group. Data of the pa-tients were collected to screen out the main influencing factors of quality of life in patients with AITL. Results The total score of quality of life before treatment was（69.32±6.82）and that was（101.62± 8.65）after treatment. There were significant differences in education level, disease awareness, family income, disease recurrence, marital status, living conditions, lymphadenopathy, anemia and lactate de-hydrogenase（LDH）between SF-36≥72 group and SF-36<72 group（P<0.05）. Logistic regression analysis showed that education（β=2.225, OR=10.596, 95%CI 6.363-29.853）, disease awareness（β= 0.992, OR=3.103, 95%CI 1.256-9.285）, family income（β=2.832, OR=12.696, 95%CI 4.663-32.593）, disease recurrence（β=3.256, OR=15.526, 95%CI 3.925-28.533）, marital status（β=2.069,OR=18.516, 95%CI 4.355-30.563）, living conditions （β=2.005, OR=13.821, 95%CI 4.189-33.253）, lymphadenopathy（β=1.325, OR=10.031, 95%CI 2.133-22.683）and LDH（β=6.358, OR= 11.852, 95%CI 5.278-26.360）were the related factors of quality of life in patients with AITL（P< 0.05）. Conclusion The quality of life of patients with AITL is relatively poor. The education lev-el, disease awareness, economic income, disease recurrence, marital status, living conditions lymphade-nopathy and LDH may affect the quality of life of patients.

参考文献/References:

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备注/Memo

备注/Memo:

作者简介：闫春梅，硕士研究生，主治医师，研究方向：血液病 通信作者：闫春梅，E-mail：65970162@qq.com

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更新日期/Last Update: 2020-07-28