|本期目录/Table of Contents|

[1]王辉,陈洁,姜岳.社区居民非酒精性脂肪性肝病发生心脑血管疾病风险的双向队列研究[J].慢性病学杂志,2019,20(08):1147-1149.
　WANGHui*,CHENJie,JIANGYue.Two-way cohort study on the risk of cardiovascular and cerebrovascular diseases in community residents with non-alcoholic fatty liver disease[J].,2019,20(08):1147-1149.
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社区居民非酒精性脂肪性肝病发生心脑血管疾病风险的双向队列研究(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
20
期数:
2019年08期
页码:
1147-1149
栏目:
论　著
出版日期:
2019-07-28

文章信息/Info

Title:
Two-way cohort study on the risk of cardiovascular and cerebrovascular diseases in community residents with non-alcoholic fatty liver disease
作者:
王辉1; 2; 陈洁1; 2; 姜岳1; 2
1.首都医科大学全科医学与继续教育学院，北京 100124； 2.北京市朝阳区高碑店社区卫生服务中心，北京 100124
Author(s):
WANGHui* ; CHENJie; JIANGYue
*CollegeofGeneralPracticeandContinuingEducation,CapitalMedicalUniversity,Beijing100124,China Correspondingauthor:JIANG Yue,E-mail:redtealook9@sina.com
关键词:
非酒精性脂肪性肝; 心脑血管疾病; 双向队列研究; 社区居民
Keywords:
Nonalcoholic fatty liver;  Cardiovascular and cerebrovascular diseases;  Two-way cohort study;  Community residents
分类号:
R575.5
DOI:
-
摘要:
目的 动态监测和管理社区居民的非酒精性脂肪性肝病（NAFLD）发病情况，探讨NAFLD与心脑血管 不良事件发生的病因学关联，为NAFLD患者的管理及预防心脑血管疾病提供依据。方法 选取北京市朝阳区 高碑店地区白家楼社区居民1 800名，回顾性地收集了2007—2011年5年居民健康体检数据，并于2012—2013年 对该辖区居民随访两年，继续前瞻性收集了健康管理数据。明确连续7年中该社区居民NAFLD发病率，评估和 动态监测NAFLD患者发生心脑血管疾病的风险。结果 2006年白家楼社区居民1 800名中NAFLD患病率为 14.78%，自2007年至2013年，白家楼社区居民每年NAFLD的新发病率分别为5.59%、6.70%、1.76%、 1.87%、1.93%、3.77%、1.53%。将未患有心脑血管疾病的居民，根据是否患有NAFLD分为暴露组（207例） 和对照组（251例）。2007—2011年，暴露组心脑血管发病率为18.84%，对照组为14.74%，相对危险度（RR） 值为1.28，特异危险度（AR）值为0.28。2011—2013年，暴露组心脑血管的累积发病率为20.77%，对照组为 16.73%，RR为1.24，AR为0.24。结论 NAFLD与心脑血管疾病发病存在一定的病因联系。
Abstract:
Objective To dynamically monitor and manage the incidence of non-alcoholic fatty liver disease（NAFLD）in community residents, and to explore the etiological correlation of NAFLD and cardiovascular and cerebrovascular adverse events, and to provide evidence for management and preven-tion of cardiovascular and cerebrovascular diseases in patients with NAFLD. Methods A total of 1 800 residents of Baijialou Community in Gaobeidian District, Chaoyang District, Beijing were select-ed as subjects. The health examination data of residents in 2007-2011 were retrospectively collected. The residents of this area were followed up for two years in2012-2013, and health management data were prospectively collected. The incidence of NAFLD in this community for7 consecutive years and the risk of cardiovascular and cerebrovascular disease in patients with NAFLD were observed. Results The prevalence of NAFLD in1 800 residents of Baijialou community in 2006 was14.78%. From 2007 to 2013, the annual incidence of NAFLD in Baijialou community residents was 5.59%,6.70%, 1.76%,1.87%,1.93%,3.77%,1.53%, respectively. Residents who did not have cardiovascular and cerebrovascular diseases were divided into the exposed group（n=207）and the control group（n=251）according to whether they had NAFLD. From 2007 to 2011, the incidence of cardiovascular and cere-brovascular disease was 18.84% in the exposed group and14.74% in the control group. The relative risk （RR）value was 1.28 and the specific risk（AR）value was 0.28. From 2011 to 2013, the cumulative incidence of cardiovascular and cerebrovascular disease was 20.77% in the exposed group and16.73% in the control group, and RR was 1.24, and AR was 0.24. Conclusion There is a certain etiological correlation between NAFLD and cardiovascular and cerebrovascular diseases.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目：北京市朝阳区科技计划项目（SF1222） 作者简介：王辉，本科，副主任医师，研究方向：全科医学 通信作者：姜岳，E-mail：redtealook9@sina.com
更新日期/Last Update: 2019-07-28