|本期目录/Table of Contents|

[1]菲尔凯提·玉山江,穆叶赛·尼加提.老年急性冠状动脉综合征患者甲状腺功能与冠状动脉病变程度的相关性分析[J].慢性病学杂志,2019,20(07):963-966.
　FEIERKAITIYushanjiang,MUYESAINijiati.Correlation analysis of thyroid function and lesion of coronary artery in elderly patients with acute coronary syndrome[J].,2019,20(07):963-966.
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老年急性冠状动脉综合征患者甲状腺功能与冠状动脉病变程度的相关性分析(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
20
期数:
2019年07期
页码:
963-966
栏目:
论　著
出版日期:
2019-07-28

文章信息/Info

Title:
Correlation analysis of thyroid function and lesion of coronary artery in elderly patients with acute coronary syndrome
作者:
菲尔凯提·玉山江; 穆叶赛·尼加提
新疆自治区人民医院心内科，乌鲁木齐 830000
Author(s):
FEIERKAITIYushanjiang; MUYESAINijiati
DepartmentofCardiology, theXinjiangUygurAutonomousRegion People's Hospital,Urumqi,Xinjiang830000,China Correspondingauthor:MUYESAINijiati,E-mail:muyassar11@aliyun.com
关键词:
老年人; 急性冠脉综合征; 甲状腺功能; 冠脉病变程度
Keywords:
Elderly;  Acute coronary syndrome;  Thyroid function;  Coronary artery disease
分类号:
R541.4
DOI:
-
摘要:
目的 探讨老年急性冠状动脉综合征（Acute Coronary Syndrome，ACS）患者甲状腺功能水平与冠脉 病变严重程度的关系。方法 回顾性分析310例新疆维吾尔自治区人民医院疑似年龄≥65岁的ACS患者的基本 资料、既往史、生化指标。根据冠状动脉造影结果，分为ACS组和正常组，分析两组患者甲状腺功能状态，比 较甲状腺激素水平和ACS的关系；根据Gensini评分将ACS患者分为低分组（10~60分）124例、高分组（≥60分） 99例，比较各组甲状腺功能相关指标水平以及与Gensini评分的相关性。结果 随着Gensini评分增加，老年 ACS患者促甲状腺激素（TSH）水平升高，游离三碘甲状腺原氨酸（FT3）水平降低，Gensini评分与TSH水平 均呈正相关（r=0.308，P<0.001），与FT3水平均呈负相关（r=0.219，P=0.001）。Logistic回归分析提示 TSH、FT3水平是高Gensini评分的独立危险因素。结论 FT3降低或TSH升高可能是影响冠脉病变程度加重 的危险因素，在临床工作中对老年ACS患者进行甲状腺功能检测，早期进行干预治疗，对预防急性冠脉事件的 发生具有重要临床意义。
Abstract:
Objective To investigate the relationship between the thyroid function and the severity of coronary lesions in elderly acute coronary syndrome（ACS）patients. Methods The data such as ba-sic information, past diseases history, biochemical indicators in 310 patients aged 65 years old and over hospitalized in the Xinjiang Uygur Autonomous Region People's Hospital were retrospectively analyzed. According to coronary angiography results, the subjects were divided into ACS group and normal group. Thyroid function status of all subjects were analyzed. According to the Gensini score, the pa-tients were divided into low score group （10~60 scores）with124 cases, high score group（≥60 scores）with99 cases, in which the thyroid hormone levels were compared, and the correlation be-tween thyroid hormone and Gensini score was analyzed. Results With the increase of Gensini score, TSH level was increased, the FT3 level was decreased in the elderly ACS patients. Gensini score was positively correlated with levels of TSH（r=0.308,P<0.001）, and negatively correlated with FT3 levels（r=0.219, P=0.001）. Logistic regression analysis showed that TSH and FT3 levels were inde-pendent risk factors for high Gensini scores.Conclusion Higher TSH or lower FT3 may be a risk factor influenced severity of coronary artery disease. The thyroid function detection and early treatmentin elderly ACS patients helps to prevent from acute coronary events.

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备注/Memo

备注/Memo:
基金项目：国家自然科学基金资助项目（81760068） 作者简介：菲尔凯提·玉山江，大学本科，住院医师，研究方向：心内科 通信作者：穆叶赛·尼加提，E-mail：muyassar11@aliyun.com
更新日期/Last Update: 2019-07-28