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[1]赵义祥,余小林,程慧,等.无创正压通气治疗急性心衰伴射血分数降低患者的临床效果[J].慢性病学杂志,2020,21(09):1306-1309.
　ZHAOYi-xiang *,YUXiao-lin,CHENGHui,et al.Clinical effect of non-invasive positive pressure ventilation in patients with acute heart failure and reduced ejection fraction[J].,2020,21(09):1306-1309.
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无创正压通气治疗急性心衰伴射血分数降低患者的临床效果

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
21
期数:
2020年09期
页码:
1306-1309
栏目:
论　著
出版日期:
2020-09-28

文章信息/Info

Title:
Clinical effect of non-invasive positive pressure ventilation in patients with acute heart failure and reduced ejection fraction
作者:
赵义祥1; 余小林2; 程慧2; 郭浩强3; 李国庆2
1.石河子大学，新疆 石河子 832000； 2.新疆维吾尔自治区人民医院心内科，乌鲁木齐 830000； 3.新疆医科大学研究生院，乌鲁木齐 830000
Author(s):
ZHAOYi-xiang * ; YUXiao-lin; CHENGHui; GUOHao-qiang; LIGuo-qing
*ShiheziUniversity,Shihezi ,Xinjiang832000,China Correspondingauthor:LIGuo-qing, E-mail:xjlqg@vip.163.com;YUXiao-lin，E-mail:yuxiaolin288@163.com
关键词:
急性心力衰竭; 无创呼吸机; 持续正压通气; 双水平正压通气
Keywords:
Acute left heart failure;  Non-invasive ventilator;  Continuous positive airway pressure;  Bilevel positive airway pressure
分类号:
R271.9
DOI:
-
摘要:
目的 探讨无创正压通气（NIPPV）治疗急性心衰伴射血分数降低患者的临床效果。方法 选取2017 年9月至2020年1月新疆维吾尔自治区人民医院收治的、使用脉搏指示连续心排血量监测系统（PiCCO）的60例 急性心衰伴射血分数降低的住院患者，随机分为持续正压通气（CPAP）组和双水平正压通气（BiPAP）组，每 组30例。在常规治疗的基础上分别给予CPAP和BiPAP无创通气。治疗前后，检测并比较两组呼吸频率 （RR）、氧分压（PaO2）、二氧化碳分压（PaCO2），PiCCO监测参数[心率（HR）、平均动脉压（MAP）、每搏输 出量指数（SVI）、左心室收缩力指数（dPmax）]。结果 治疗后，两组患者RR和PaCO2低于本组治疗前， PaO2高于治疗前，且组间PaO2和PaCO2比较，差异均有统计学意义（P<0.05）。治疗后，两组患者SVI较治疗 前升高，HR、MAP降低，差异均有统计学意义（P<0.05）。结论 CPAP和BiPAP无创通气治疗急性心衰伴 射血分数降低患者有效，且BiPAP无创通气更有助于改善患者呼吸功能。
Abstract:
Objective To explore the clinical effect of non-invasive positive pressure ventilation（NIP-PV）in the treatment of acute left heart failure combined with reduced ejection fraction. Methods Totally60 patients with acute heart failure and reduced ejection fraction who used the PiCCO monitoring system from September 2017 to January 2020 were selected as the research subjects and randomlydi-vided into the continuous positive airway pressure（CPAP）group（n=30）and bilevel positive airway pressure（BiPAP）group（n=30）. On the basis of conventional treatment, the above patients were giv-en CPAP and BiPAP, respectively. Respiratory rate（RR）, partial pressure of oxygen（PaO2）, partial pressure of carbon dioxide（PaCO2）, and PiCCO monitoring parameters [heart rate（HR）, mean arteri-al pressure（MAP）, stroke output index（SVI）, left ventricular contractility index（dPmax）] were measured before and after treatment.Results After treatment, the levels of RR and PaCO2 were de-creased in the two groups, and levels of PaO2 were increased, and there were significant differences in PaO2 and PaCO2 between the two groups（P<0.05）. After treatment, the levels of SVI in the two groups were increased, and the levels of HR and MAP were decreased, and the differences were sta-tistically significant （P<0.05）. Conclusion Both CPAP and BiPAP are effective in treating patients with acute heart failure and reduced ejection fraction, and BiPAP is more helpful for improving pa-tients’respiratory function.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目：新疆维吾尔自治区自然科学基金（2018D01C111） 作者简介：赵义祥，硕士研究生，研究方向：冠心病基础与临床 通信作者：李国庆，E-mail: xjlqg@vip.163.com；共同通信作者：余小林，E-mail: yuxiaolin288@163.com
更新日期/Last Update: 2020-09-28