|本期目录/Table of Contents|

[1]杨月辉,周秀菊,侯媛,等.糖尿病合并高血压患者血尿酸、同型半胱氨酸水平变化及意义[J].慢性病学杂志,2019,20(08):1129-1132.
　YANGYue-hui *,ZHOUXiu-ju,HOUYuan,et al.Changes and significance of serum uric acid and homocysteine levels in patients with diabetes mellitus and hypertension[J].,2019,20(08):1129-1132.
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糖尿病合并高血压患者血尿酸、同型半胱氨酸水平变化及意义(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
20
期数:
2019年08期
页码:
1129-1132
栏目:
论　著
出版日期:
2019-07-28

文章信息/Info

Title:
Changes and significance of serum uric acid and homocysteine levels in patients with diabetes mellitus and hypertension
作者:
杨月辉1; 周秀菊2; 侯媛2; 李晶珠3
1.东营市美年大健康健康管理有限公司东营综合门诊部，山东 东营 257000； 2.山东省东营市胜利油田中心医院，山东 东营 257000； 3.内蒙古自治区呼伦贝尔市额尔古纳市中蒙医院，内蒙古 呼伦贝尔 022191
Author(s):
YANGYue-hui * ; ZHOUXiu-ju; HOUYuan; LIJing-zhu
*DongyingComprehensiveOutpatient Department,DongyingMeinianHealth Management Co.LTD., Dongying,Shandong257000,China Correspondingauthor:ZHOUXiu-ju,E-mail:zxyyzxj@163.com
关键词:
糖尿病; 高血压; 血尿酸; 同型半胱氨酸
Keywords:
Diabetes mellitus;  Hypertension;  Blood uric acid;  Homocysteine
分类号:
R587.1；R544.1
DOI:
-
摘要:
目的 探讨糖尿病合并高血压患者血尿酸、同型半胱氨酸（Hcy）水平变化及意义。方法 选择2018年 1—12月收治的2型糖尿病合并高血压病患者30例为观察组，单纯糖尿病患者30例为糖尿病组，另选择健康体检 者30例为对照组。比较三组血尿酸、Hcy、血脂水平，并分析糖尿病合并高血压患者血尿酸与Hcy水平的相关 性。结果 观察组尿酸、Hcy水平显著高于糖尿病组与对照组，糖尿病组显著高于对照组，差异有统计学意义 （P<0.05）。观察组总胆固醇（TC）、甘油三酯（TG）水平显著高于糖尿病组与对照组，高密度脂蛋白胆固醇 （HDL-C）水平显著低于糖尿病组与对照组，糖尿病组TC、TG水平显著高于对照组，HDL-C水平显著低于对 照组，差异有统计学意义（P<0.05）。观察组患者尿酸与Hcy呈显著正相关（r=0.840，P<0.05）。结论 糖尿 病合并高血压患者血尿酸、Hcy水平显著升高，并且两者存在明显的正相关的关系。
Abstract:
Objective To discuss the changes of serum uric acid and homocysteine（Hcy）levels in pa-tients with diabetes mellitus and hypertension. Methods Thirty patients with type2 diabetes mellitus and hypertension diagnosed and treated in hospital from January to December 2018 were selected as the observation group; thirty patients with simple diabetes mellitus were in the diabetes group; another 30 healthy persons were selected as control group. The levels of serum uric acid, Hcy and lipid in three groups were compared. The correlation between serum uric acid and Hcy levels in diabetic pa-tients with hypertension was analyzed. Results The levels of uric acid and Hcy in the observation group were significantly higher than those in the diabetic group and the control group, while those in the diabetic group were significantly higher than those in the control group（P<0.05）. The levels of TC and TG in the observation group were significantly higher than those in the diabetic group and the control group; the level of HDL-C in the observation group was significantly lower than that of diabet-ic group and control group（all P<0.05）. There were significant differences in TC, TG and HDL-C between the diabetic group and the control group（all P<0.05）. There was a positive correlation be-tween uric acid and Hcy in the observation group （r=0.840, P<0.05）. Conclusion The levels ofserum uric acid and Hcy in diabetic patients with hypertension are significantly increased, and there is a significant positive correlation between them.

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备注/Memo

备注/Memo:
作者简介：杨月辉，大学本科，主治医师，研究方向：心血管 通信作者：周秀菊，E-mail：zxyyzxj@163.com
更新日期/Last Update: 2019-07-28