|本期目录/Table of Contents|

[1]杨维,张悟棠,孔永梅.术前CRP水平与冠状动脉旁路移植术患者预后的关系[J].慢性病学杂志,2019,20(10):1455-1458.
　YANGWei,ZHANGWu-tang,KONGYong-mei.Relationship between preoperative CRP level and prognosis of patients undergoing coronary artery bypass grafting[J].,2019,20(10):1455-1458.
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术前CRP水平与冠状动脉旁路移植术患者预后的关系

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
20
期数:
2019年10期
页码:
1455-1458
栏目:
论　著
出版日期:
2019-10-28

文章信息/Info

Title:
Relationship between preoperative CRP level and prognosis of patients undergoing coronary artery bypass grafting
作者:
杨维; 张悟棠; 孔永梅
山西省心血管病医院，太原 030024
Author(s):
YANGWei; ZHANGWu-tang; KONGYong-mei
ShanxiCardiovascular Hospital,Taiyuan030024,China Correspondingauthor: ZHANG Wu-tang,E-mail:zwt13327510617@sina.com
关键词:
冠心病; C反应蛋白; 冠状动脉旁路移植术; 预后
Keywords:
Coronary heart disease;  C-reactive protein;  Coronary artery bypass grafting;  Prognosis
分类号:
R654.2
DOI:
-
摘要:
目的 探讨术前C反应蛋白（C-reactive protein，CRP）水平对冠状动脉旁路移植术（Coronary artery bypass grafting，CABG）后早期和晚期死亡率的预测价值。方法 采用前瞻性研究分析2011年1月—2018年 12月山西省心血管病医院收治的1 800例行CABG术的冠心病患者的临床资料及术前24h内血清CRP水平，并 分析术前CRP水平与CABG术后早期和晚期死亡率的关系。随访过程中有106例患者失访。结果 发现术前 CRP水平大于10mg/L时早期死亡率增加，而大于5 mg/L时晚期死亡率增加，并且经过多因素COX比例风险 模型校正多项已知危险因素后，术前CRP水平仍是CABG术后早期及晚期死亡的独立危险因素。结论 术前 CRP水平是CABG术后危险分层的强有力的炎症指标，对于CABG术后预后的评价具有重要指导意义。
Abstract:
Objective To analyze the predictive value of preoperative C-reactive protein（CRP） levels for early and late mortality in paitents with coronary artery bypass grafting （CABG）. Methods From January 2011 to December 2018, 1 800 patients with coronary heart disease who underwent CABG surgery in Shanxi Cardiovascular Hospital were continuously selected, and their clinical data and serum CRP levels within 24 hours before surgery were collected. The re-lationship between early and long-term mortality of CRP levels were analyzed. Results Totally 106 patients were unavailable for follow-up. The results showed that early mortality increased when preoperative CRP level was greater than 10 mg/L, and late mortality increased when pre-operative CRP level was greater than 5 mg/L. After multiple risk factors were corrected by multivariate COX proportional hazard models, preoperative CRP level was still an independent risk factor for early and late death after CABG. Conclusion Preoperative CRP level can be used as a powerful inflammatory marker for risk stratification after CABG, and it is an impor-tant guiding factor for the evaluation of prognosis after CABG.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介：杨维，硕士，研究方向：心脏重症医学 通信作者：张悟棠，E-mail：zwt13327510617@sina.com
更新日期/Last Update: 2019-10-28