|本期目录/Table of Contents|

[1]杨富胜.依达拉奉联合奥拉西坦治疗高血压脑梗死的疗效及对神经功能的影响[J].慢性病学杂志,2018,(11):1499-1501.
 YANG Fu-sheng.Effect of edaravone combined with oxiracetam on acute cerebral infarction and its effect on neurological function[J].,2018,(11):1499-1501.
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依达拉奉联合奥拉西坦治疗高血压脑梗死的疗效及对神经功能的影响(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2018年11期
页码:
1499-1501
栏目:
论 著
出版日期:
2018-11-30

文章信息/Info

Title:
Effect of edaravone combined with oxiracetam on acute cerebral infarction and its effect on neurological function
作者:
杨富胜
鄢陵县中心医院,河南鄢陵461200
Author(s):
YANG Fu-sheng
Yanling Central Hospital, Henan 461200, China Corresponding author: YANG Fu-Sheng, E-mail: 1246840772@qq.com
关键词:
依达拉奉奥拉西坦高血压脑梗死
Keywords:
Edaravone Hypertension Cerebral infarction
分类号:
R544
DOI:
-
摘要:
目的探讨依达拉奉联合奥拉西坦治疗高血压脑梗死的临床疗效及对神经功能的影响。方法选取 2017 年1 月—2018 年1 月鄢陵县中心医院80 例就诊的高血压脑梗死患者,随机分为对照组和观察组,每组 40例。对照组给予奥拉西坦治疗,观察组在对照组的治疗基础上给予依达拉奉治疗,均治疗两周后观察两组的美 国卒中量表评分(NHISS)、蒙特利尔认知评估量表(MoCA) 评分、临床疗效及不良反应。结果治疗后观察 组的NHISS 低于对照组(P<0.05),治疗后观察组的MoCA 评分高于对照组(P<0.05)。治疗后观察组的临床 疗效(90.00%) 优于对照组(67.50%), 差异有统计学意义(P<0.05)。治疗后观察组不良反应发生率 (7.50%) 低于对照组(15.00%),差异有统计学意义(P<0.05)。结论依达拉奉联合奥拉西坦治疗高血压脑 梗死疗效可靠,可明显改善患者的神经缺损程度和认知水平。
Abstract:
Objective To investigate the clinical efficacy of edaravone combined with oxiracetam in the treatment of hypertensive cerebral infarction and its effect on nervous function. Methods Totally 80 patients with hypertensive cerebral infarction hospitalized in Yanling Central Hospital from January 2017 to January 2018 were randomly divided into control group and observation group, each with 40 cases. The control group was treated with oxiracetam, and the observation group was treated with edaravone on the basis of the control group. After treatment for two weeks, the American Stroke Scale (NHISS) , Montreal Cognitive Assessment Scale (MoCA) , clinical efficacy and adverse reactions were observed. Results After treatment, compared to the control group, the NHISS score was lower (P<0.05) , and the MoCA score was higher in the observation group (all P<0.05) . After treatment, the clinical efficacy of the observation group (90.00%) was better than that of the control group (67.50%)(P<0.05) . The incidence of adverse reactions in the observation group (7.50%) was lower than that in the control group (15.00%)(P<0.05) . Conclusion The treatment of edaravone combined with oxiracetam is effective in the treatment of hypertensive cerebral infarction, and can improve the degree of nerve defect and cognitive level of patients.

参考文献/References:


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备注/Memo

备注/Memo:
作者简介:杨富胜,大学本科,副主任医师,研究方向:神 经重症 通信作者:杨富胜,E-mail:1246840772@qq.com
更新日期/Last Update: 2018-11-30