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[1]周立辉,皮林,任文林,等.ST 段抬高型心肌梗死患者二级预防药物长期依从性调查[J].慢性病学杂志,2018,(11):1473-1475.
　ZHOU Li-hui,PI Lin,REN Wen-lin,et al.Long-term adherence of secondary prevention medication in ST-elevation myocardial infarction patients[J].,2018,(11):1473-1475.
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ST 段抬高型心肌梗死患者二级预防药物长期依从性调查(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2018年11期
页码:
1473-1475
栏目:
论　著
出版日期:
2018-11-30

文章信息/Info

Title:
Long-term adherence of secondary prevention medication in ST-elevation myocardial infarction patients
作者:
周立辉;  皮林;  任文林;  张凤英;  李莉
北京市垂杨柳医院心脏中心，北京100022
Author(s):
ZHOU Li-hui;  PI Lin;  REN Wen-lin;  ZHANG Feng-ying;  LI Li
Heart Center, Beijing Chuiyangliu Hospital, Beijing 100022 Corresponding author: PI Lin, E-mail: pilindoctor@126.com
关键词:
冠心病; ST 段抬高型心肌梗死; 二级预防; 依从性; 停药
Keywords:
Coronary heart disease;  ST- elevation myocardial infarction;  Secondary prevention;  Adherence;  Medication discontinuation
分类号:
R542.2
DOI:
-
摘要:
目的了解ST 段抬高型心肌梗死（ST-elevation myocardial infarction，STEMI） 患者二级预防药物 的长期依从性并分析其原因。方法采用回顾性研究方法，对连续入组的723 例STEMI患者3 年后的二级预防 药物依从性进行随访观察，并分析其影响因素。结果入组3年后患者服用阿司匹林、血管紧张素转化酶抑制剂 （ACEIs） /血管紧张素受体拮抗剂（ARB）、β-受体阻滞剂、他汀类药物的使用比例分别为88.12%、45.37%、 68.83%、69.60%；未服用阿司匹林的患者的停药原因中，禁忌证占6.49%，不能耐受的占16.88%，自行停药占 66.23%，未处方占5.19%，其他占5.19%；未服用ACEIs/ARB 的患者的停药原因中，禁忌证占4.80%，不能耐 受占3.95%，自行停药占29.94%，未处方的占58.76%，其他占2.54%；未服用β-受体阻滞剂的患者的停药原因 中，禁忌证占5.44%，不能耐受的占4.95%，自行停药的占42.57%，未处方的占46.53%，其他占0.50%；未服用 他汀类药物的患者的停药原因中，禁忌证占0.51%，不能耐受的占3.55%，自行停药的占63.45%，未处方的占 30.49%，其他占2.03%。结论STEMI患者二级预防药物的长期依从性偏低，患者认知（自行停药） 和医生因 素（未处方） 是造成患者停药的主要因素。
Abstract:
Objective To evaluate long-term adherence of secondary prevention medication in ST-elevation myocardial infarction （STEMI） patients and to explore the corresponding reasons. Methods Totally 723 STEMI patients on secondary prevention medication were enrolled consecutively in a retrospective study, after follow-up of 3 years, medication adherence was evaluated and potential contributing factors were identified. Results After follow up of 3 years, the proportion of patients who still took aspirin, ACEIs/ARB, beta-blockers or statins were 88.12%, 45.37%, 68.83%, 69.60% respectively. For those patients not taking aspirin, 6.49% of them was because of contraindications, 16.88% was due to intolerance, 66.23% was on their own will, 5.19% was due to no prescription and 5.19% was due to other unspecified reasons. For ACEIs/ARB, the figures were 4.80% , 3.95% , 29.94% , 58.76% , and 2.54% respectively. For beta- blockers, the figures were 5.45% , 4.95% , 42.57% , 46.53% , and 0.50% respectively. For statins, the figures are 0.51% , 3.55% , 63.45% , 30.46% , and 2.03% respectively. Conclusion Long term compliance of secondary prevention in STEMI patients is low. Patients’cognition and physicians are among the reasons for medication discontinuation.

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备注/Memo

备注/Memo:
基金项目：北京市科委立项课题（Z171100001017256） 作者简介：周立辉，硕士研究生，主治医师，研究方向：心血管病学 通信作者：皮林，E-mail：pilindoctor@126.com
更新日期/Last Update: 2018-11-30