|本期目录/Table of Contents|

[1]黄双双,凌敏.超重与慢性阻塞性肺疾病症状程度及肺功能分级的相关性[J].慢性病学杂志,2020,21(04):593-595.
点击复制

超重与慢性阻塞性肺疾病症状程度及肺功能分级的相关性

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
21
期数:
2020年04期
页码:
593-595
栏目:
专题报道
出版日期:
2020-04-28

文章信息/Info

Title:
-
作者:
黄双双1; 凌敏2
1.新疆石河子大学医学院，新疆 石河子 832000； 2.新疆维吾尔自治区人民医院呼吸与危重症医学二科，乌鲁木齐 830000
Author(s):
-
关键词:
超重; 慢性阻塞性肺疾病; 症状程度; 肺功能分级; 体质量指数
Keywords:
-
分类号:
R563.9
DOI:
-
摘要:
目的 探讨超重与慢性阻塞性肺疾病（COPD）症状程度及肺功能分级的相关性，为临床研究提供参 考。方法 选取2017年6月—2019年6月新疆维吾尔自治区人民医院门诊及住院的332例COPD患者，其中正 常体质量（18.5 kg/m 2 ≤BMI<23.9kg/m 2）COPD患者137例为对照组，超重（24 kg/m 2 ≤BMI<27.9 kg/m 2） COPD患者195例为观察组。记录并比较两组患者年龄、性别、身高、体质量、吸烟史、BMI、症状程度及肺功 能分级。比较对照组和观察组COPD患者症状及肺功能分级有无差异，运用Spearman相关分析超重与COPD症 状及肺功能分级的相关性。结果 两组改良版英国医学研究会呼吸问卷（mMRC）评分比较，差异有统计学意 义（P<0.05）。Spearman相关性分析结果显示，在对照组和观察组中，BMI与症状程度成负相关（rs=-0.154， P<0.01），观察组症状比对照组症状轻。两组的肺功能分级差异无统计学意义（rs=-0.074，P>0.05）。结论 超重COPD患者比正常体质量COPD患者症状轻，超重与肺功能分级无关。
Abstract:
-

参考文献/References:

[1] Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary [J]. Am J Respir Crit Care Med, 2017,195:557-582. [2] López-Campos JL, Soler-Catalu?a JJ, Miravitlles M, et al. (2019). Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease: the gold science committee report 2019 [J]. Eur Respir J, 2019,53 (5):1900164. [3] Zhou M, Wang H, Zeng X, et al. Mortality, morbidity,and risk factors in China and its provinces,1990-2017:a systematic analysis for the global burden of disease study 2017[J]. Lancet, 2019,394(10204):1145-1158. [4] L?kke A, Hilberg O, T?nnesen P, et al. Direct and indi-rect economic and health consequences of COPD in Den-mark: a national register- based study: 1998-2010 [J]. BMJ Open,2014,4(1):e004069. [5] Guo Y, Zhang T, Wang Zet al. Body mass index and mortality in chronic obstructive pulmonary disease: a dose-response meta-analysis [J]. Medicine (Baltimore), 2016,95 (28):e4225. [6] Zhenchao W, Dong Y, Zhengwei G,et al. Body mass in-dex of patients with chronic obstructive pulmonary disease is associated with pulmonary function and exacerbations: a retrospective real world research [J]. J Thorac Dis, 2018, 10(8):5086-5099. [7] 中华医学会内分泌学分会肥胖学组.2011CES中国成人肥胖症防 治专家共识[J].中华内分泌代谢代谢杂志[J],2011,27(9):711-717. [8] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺 疾病基层诊疗指南（2018年）[J].中华全科医师杂志,2018,17 (11):856-870. [9] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞性肺 疾病诊治指南(2013年修订版) [J].中华结核和呼吸杂志,2013, 36(4):255-264. [10] Li Y, Yang L, Wang L,et al. Burden of hypertension in China:a nationally representative survey of174 621 adults [J]. Int J Cardiol, 2017,15(227):516-523. [11] GBD 2015 Chronic Respiratory Disease Collaborators. Global, regional,and national deaths,prevalence,disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015:a systematic analysis for the Global Burden of Dis-ease Study 2015[J]. Lancet Respir Med, 2017,5:691-706. [12] Chen M, Li B, Sang N,et al. Particulate matter(PM2.5) exposure season- dependently induces neuronal apoptosis and syn-aptic injuries [J]. J Environ Sci, 2017,54:336-345. [13] Jo YS, Kim YH, Lee JY, et al. Impact of BMI on exac-erbation and medical care expenses in subjects with mild to moderate airflow obstruction [J]. INT J CHRONIC OB-STR,2018,27(13):2261-2269. [14] Cao C, Wang R, Wang J,et al. Body mass index and mortality in chronic obstructive pulmonary disease: a meta analysis [J]. PLoS One, 2012,7(8):e43892. [15] Wang C, Xu J, Yang L,et al. Prevalence and risk factors of chronic obstructive pulmonary disease in China (the Chi-na Pulmonary Health [CPH] study): a national cross-sec-tional study [J]. Lancet, 2018,391(10131):1706-1717. [16] Paul S, Saskia , Foerster J,et al. Overweight is a predic-tor of long-term survival in hospitalized patients with exac-erbations of COPD [J]. Respir Med, 2016,116:59-62. [17] Schols AM, Slangen J, Volovics L,et al. Weight loss is a reversible factor in the prognosis of chronic obstructive pulmonary disease [J]. Am J Respir Crit Care Med, 1998, 157(6 Pt1):1791-1797. [18] Kwan HY, Maddocksn M, Nolan C,et al. The prognos-tic significance of weight loss in chronic obstructive pulmo-nary disease- related cachexia:a prospective cohort study [J]. J Cachexia Sarcopenia Muscle, 2019,10(6):1330-1338.

备注/Memo

备注/Memo:
作者简介：黄双双，在读研究生，研究方向：慢性阻塞性 肺疾病 通信作者：凌敏，E-mail：lingmin1121@163.com
更新日期/Last Update: 2020-04-28