|本期目录/Table of Contents|

[1]王贞,陈和清.系统性红斑狼疮患者抑郁症发生情况及健康教育对其影响[J].慢性病学杂志,2018,(01):12-14.
 WANGZhen*,CHENHe-qing.High prevalence of depression in systemic lupus erythematosus patients and the value of health education[J].,2018,(01):12-14.
点击复制

系统性红斑狼疮患者抑郁症发生情况及健康教育对其影响(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2018年01期
页码:
12-14
栏目:
论著
出版日期:
2018-01-30

文章信息/Info

Title:
High prevalence of depression in systemic lupus erythematosus patients and the value of health education
作者:
王贞1陈和清2
1.福建省漳州卫生职业学院,福建 漳州 363000; 2.福建省福建医科大学附属漳州市医院,福建 漳州 363000
Author(s):
WANGZhen* CHENHe-qing
*Zhangzhou HealthVocationalCollege, Zhangzhou, Fujian363000,China Correspondingauther:WANGZhen ,E-mail:410189327@qq.com
关键词:
系统性红斑狼疮抑郁症病程疾病活动度健康教育
Keywords:
Systemic lupus erythematosus Depression Disease duration Disease activityHealth education
分类号:
R593.24
DOI:
-
摘要:
目的 探讨系统性红斑狼疮(SLE)患者高发抑郁倾向,并判断患者疾病活动度及病程与抑郁症的相关 性,及合理健康教育对患者抑郁症程度的影响。方法 选择52例SLE患者及52例健康对照者作为研究对象。 SLE患者根据系统性红斑狼疮疾病活动性指数(SLEDAI)分为活动组27例和非活动组25例;病程≥5年的 24例,病程<5年的28例。采用贝克抑郁量表(BDI)评分法比较各组之间的BDI分值,并比较抑郁症发病率。 结果 SLE组和对照组抑郁症发病率分别为19.23%和5.76%,差异有统计学意义(P<0.05);两组BDI评分分 别为(11.90±4.62)和(6.00±3.02)分(P<0.01)。SLE组中,病程≥5年组和<5年组BDI评分分别为 (14.13±4.23)和(10.00±4.13)分(P=0.001);疾病活动组与非活动组BDI评分分别为(14.70±3.66)和(8.88± 3.55)分(P<0.001);健康教育前后BDI评分分别为(11.90±4.62)和(8.58±4.93)分(P<0.01)。结论 SLE 患者高发抑郁症,并且抑郁症程度与SLE病程长短及疾病活动度有关;合理的健康教育对患者十分必要。
Abstract:
Objective To study high- risk tendency of depression in systemic lupus erythematosus (SLE)patients and the correlation with disease activity and disease duration, and to find out the value of reasonable health education for SLE patients with depression. Methods Totally52 SLE patients and 52 healthy cases were selected into this study. The SLE patients were divided into active group (n=27)and inactive group(n=25)according to the activity index of SLE. The SLE patients were di-vided into ≥5 years group(n=24)and <5 years group(n=28)according to the course of disease. The scores of Beck Depression inventory(BDI)and the incidence of depression in above group were compared. Results The prevalence of depression and BDI score in SLE patients were significantly higher than those in the healthy controls(19.2% vs.5.8%,P<0.05; 11.90±4.62 vs. 6.00±3.02, P< 0.001). The BDI score in disease course ≥5 years group was higher than that in the <5 years group (14.13±4.23 vs. 10.00±4.13, P<0.001). The BDI score in active group was higher than that in inac-tive group (14.70±3.66 vs. 8.88±3.55, P<0.001). The BDI score was significantly decreased after health education(11.90±4.62 vs. 8.58±4.93, P<0.001). Conclusion SLE patients have higher inci-dence of depression which associated with SLE disease activity and course. The rational health educa-tion is essential for SLE patients.

参考文献/References:

[1] Amercian Psychiatric Association. Diagnostic and statistical manual of mental disorders (Fourth edition. DSM- IV) [M]. Washington, DC: Amercian Psychiatric Association, 1994,317-391.
[2] van Exel E, Jacobs J, Korswagen LA, et al.Depression insystemic lupus erythematosus, dependent on or indepen-dent of severity of disease [J]. Lupus, 2013,22(14):1462-1469.
[3] Maneeton B, Maneeton N, Louthrenoo W. Prevalence and predictors of depression in patients with systemic lupus ery-thematosus: a cross-sectional study [J]. Neuropsychiatr Dis Treat,2013,9:799-804.
[4] Mok CC, Chan KL, Cheung EF,et al. Suicidal ideation in patients with systemic lupus erythematosus: incidence and risk factors [J]. Rheumatology (Oxford), 2014,53(4): 714-721.
[5] Karimifar M, Sharifi I, Shafiey K. Anti-ribosomal P anti-bodies related to depression in early clinical course of sys-temic lupus erythematosus [J]. J Res Med Sci, 2013,18 (10):860-864.
[6] Shen B, Tan W, Feng G,et al. The correlations of dis-ease activity, socioeconomic status, quality of life, and de-pression/anxiety in Chinese patients with systemic lupus er-ythematosus [J]. Clin Dev Immunol,2013:270878.
[7] 周凤艳,吴红莲,朱小玲.系统性红斑狼疮女性病人压力源与抑郁 情绪的相关性研究[J].护理研究,2016,30(6):718-721.
[8] Xu J, Cheng YQ, Chen B,et al. Depression in systemic lupus erythematosus patients is associated with link-poly-morphism but not methylation status of the5HTT promot-er region [J]. Lupus, 2013,22(10):1001-1010.
[9] 李双玉,王华.系统性红斑狼疮初诊女性患者焦虑抑郁状态的心 理干预[J].现代医药卫生,2017,33(5):763-765.
[10] 林晓霞,李双.个体化心理干预对系统性红斑狼疮患者心理健康 水平的影响[J].中外医学研究,2017,15(24):96-98.

备注/Memo

备注/Memo:
作者简介:王贞,硕士研究生,讲师,研究方向:风湿血液病学,教育学
通信作者:王贞,E-mail:410189327@qq.com
更新日期/Last Update: 2018-01-30