|本期目录/Table of Contents|

[1]吴迪,白志军,李尚鑫.大分割和常规分割放疗对骨转移瘤疼痛的疗效研究[J].慢性病学杂志,2017,(09):966-968.
　WU Di,BAI Zhi-jun,LI Shang-xin.Effect of big fractionated radiotherapy and conventional fractionation radiotherapy on cancer pain of patients with metastatic bone tumors[J].,2017,(09):966-968.
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大分割和常规分割放疗对骨转移瘤疼痛的疗效研究(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2017年09期
页码:
966-968
栏目:
论著
出版日期:
2017-09-23

文章信息/Info

Title:
Effect of big fractionated radiotherapy and conventional fractionation radiotherapy on cancer pain of patients with metastatic bone tumors
作者:
吴迪;  白志军;  李尚鑫
赤峰市医院放疗科，内蒙古赤峰024000
Author(s):
WU Di;  BAI Zhi-jun;  LI Shang-xin
Department of radiotherapy, Chifeng City Hospital, Chifeng, Inner Mongolia 024000, China Corresponding author: WU Di, E-mail: gabrut@sina.com
关键词:
大分割放疗; 常规分割放疗; 骨转移瘤; 止痛效果
Keywords:
Big fractionated radiotherapy;  Conventional fractionation radiotherapy;  Metastatic bone tumors;  Analgesic effect
分类号:
R273
DOI:
-
摘要:
目的对大分割放疗与常规分割放疗两种方式缓解因恶性肿瘤骨转移造成的疼痛的效果进行对比分析。 方法选取赤峰市医院2014 年1 月至2016 年12 月进行放疗的48 例恶性肿瘤骨转移患者作为研究对象，随机分 为观察组与对照组，每组24例。观察组患者采用大分割放疗方案进行治疗，对照组患者采用常规分割放疗方案进 行3 周放疗，对比两组患者治疗前后的视觉模拟评分法（VAS） 疼痛评分、疼痛减轻程度及止痛起效时间。结 果两组患者治疗前VAS 疼痛评分比较，差异无统计学意义（P>0.05）；治疗后观察组（3.52±0.22） 分，对照 组（3.64±0.25） 分，均较治疗前明显降低（P<0.05），但两组间差异无统计学意义（P>0.05）。观察组止痛有效 率为79.17%，对照组为75.00%，差异无统计学意义（P>0.05）；观察组的止痛起效时间在1 周以内的有18 例 （75.00%），对照组11 例（45.83%），差异有统计学意义（P<0.05）。结论大分割放疗比常规分割放疗在治疗 恶性肿瘤骨转移癌痛的效果起效快，在临床适当情况下可首选大分割放疗的方式。
Abstract:
Objective To compare the clinical effect of big fractionated radiotherapy and conventional fractionation radiotherapy on cancer pain of patients with metastatic bone tumors. Methods Totally 48 patients with metastatic bone tumors in Chifeng City Hospital were divided into experimental group and control group according to the random alphabet, 24 cases in each group. The experimental group received the treatment of big fractionated radiotherapy. The control group received conventional radiotherapy. Coureses of treatment were all three weeks. VAS pain scores and degree of pain relief and onset time were compared between the two groups before and after treatment. Results The VAS pain scores of two groups were no significant difference （P>0.05） . After treatment, the VAS pain score in experimental group and control group was （3.519±0.218） and （3.643±0.248） points, were all significantly lower than those of before treatment （all P<0.05） , but there was no significant difference between the two group （P>0.05） . The pain relieving rate of experimental group and control group was significantly different （79.54% vs. 81.81%, P>0.05） . Onset time in 18 cases of patients （75.00%） of experimental group and 11 cases of patients （45.83%） of control group was less than 1 week, there was significantly different （P<0.05） . Conclusions Big fractionated radiotherapy has faster effect in patients with metastatic bone tumors compared to conventional fractionation radiotherapy and should be the first choice for clinical treatment.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介：吴迪，研究生，副主任医师，研究方向：骨转移瘤，乳腺癌 通信作者：吴迪，E-mail:gabrut@sina.com
更新日期/Last Update: 2017-09-30