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《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:

期数:

2017年08期

页码:

847-850

栏目:

论著

出版日期:

2017-09-07

文章信息/Info

Title:

Clinical observation on self-made Yangwei decoction combined with domperidone for treatment of diabetic gastroparesis patients

作者:

阎玲

北京市房山区中医医院脾胃病科，北京102400

Author(s):

YAN Ling

Department of Spleen and Stomach Diseases, Fangshan Traditional Chinese Medical Hospital, Beijing 102400, China Corresponding author: YAN Ling, E-mail: yanling5510@163.com

关键词:

糖尿病; 胃轻瘫; 中西医结合

Keywords:

Key words: Diabetes mellitus;  Gastroparesis;  Combination of Chinese traditional and western medicine

分类号:

R587.1

DOI:

-

摘要:

目的观察中西医结合治疗糖尿病胃轻瘫的疗效，为改善糖尿病性胃轻瘫临床症状提供理伦依据。方法 选择2014 年7 月—2017 年7 月北京市房山区中医医院门诊及住院处的146 例糖尿病胃轻瘫患者作为研究对象， 随机分为对照组和治疗组，每组73例。对照组常规控制血糖，并口服多潘立酮10 mg，3次/d。治疗组在对照组的 基础上给予自拟养胃汤治疗，1 剂/d，水煎取汁300 ml，分2 次温服。治疗4 周后，比较两组临床疗效、症状积 分、血糖及胃肠动力指标。结果4 周后治疗组总有效率91.78%，对照组总有效率67.12%，差异有统计学意义 （P<0.05）；治疗组在改善胃脘胀满、早饱、恶心、呕吐、食欲不振、嗳气等症状方面明显优于照组，差异均有统 计学意义（P＜0.05 或P＜0.01）。治疗组在治疗后餐后2 h 血糖及糖化血红蛋白水平均低于对照组，差异均有统 计学意义（均P＜0.05）。胃肠动力改善方面，治疗组总有效率为89.04%，显著高于对照组的63.01%，差异有统计 学意义（P<0.05）。结论中西医结合治疗糖尿病性胃轻瘫能够改善临床症状，提高治疗效果，值得临床应用。

Abstract:

Objective To observe the efficacy of combination of Chinese traditional and western medicine on diabetic gastroparesis. Methods Totally 146 cases with diabetic gastroparesis from Fangshan Traditional Chinese Medical Hospital during July, 2014 to July, 2017 were collected and divided into the observation group and the control group, 73 cases in each group. The control group were given domperidone （10 mg, 3 times per day） with regular treatment on blood glucose. On the basic treatment of the control group, the observation group were given self- made Yangwei decoction （1 agent per day, 300 ml） . After 4 weeks, clinical efficacy, symptom score, blood glucose and gastrointestinal motility index were compared between the two groups. Results The total effective rate was 91.78% in the observation group and 67.12% in the control group, P<0.05. The observation group was superior to the control group on improving the symptoms of epigastric fullness, early satiety, nausea, vomiting, loss of appetite and belching, and the differences were all significant （P<0.05 or P<0.01） . The levels of blood glucose and glycosylated hemoglobin in the observation group were significantly lower than those in the control group （P<0.05） . The total effective rate was 89.04% in the observation group and 63.01% in the control group. The total effective rate on gastrointestinal motility of the observation group was significantly higher than that of the control group （89.04% vs. 63.01%, P<0.05） .Conclusion For patients with diabetic gastroparesis, the integrative traditional Chinese and western medicine can improve the clinical symptoms and efficacy, and it is worthy of clinical application.

参考文献/References:

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备注/Memo

备注/Memo:

基金项目：北京市房山区中医医院科研项目（K-2014-y05）
作者简介：阎玲，硕士研究生，主治医师，研究方向：中医脾胃病
通信作者：阎玲，E-mail: yanling5510@163.com

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更新日期/Last Update: 2017-09-08