|本期目录/Table of Contents|

[1]陈桂娥,庞绍衡,马海波,等.使用动态增强扫描及扩散加权成像对前列腺良恶性疾病的鉴别诊断研究[J].慢性病学杂志,2017,(07):717-719.
　CHEN Gui-e,PANG Shao-heng,MA Hai-bo,et al.Identification of benign and malignant prostatic diseases by dynamic contrast-enhanced MRI and diffusion-weighted imaging[J].,2017,(07):717-719.
点击复制

使用动态增强扫描及扩散加权成像对前列腺良恶性疾病的鉴别诊断研究(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2017年07期
页码:
717-719
栏目:
论著
出版日期:
2017-08-08

文章信息/Info

Title:
Identification of benign and malignant prostatic diseases by dynamic contrast-enhanced MRI and diffusion-weighted imaging
作者:
陈桂娥; 庞绍衡; 马海波; 李德朝; 廖文伦
贺州市中医医院，广西贺州542899
Author(s):
CHEN Gui-e;  PANG Shao-heng;  MA Hai-bo;  LI De-zhao;  LIAO Wen-lun
Hezhou Traditional Chinese Medicine Hospital, Hezhou, Guangxi 542899, China Corresponding author: CHEN Gui-e, E-mail: lilian1608@163.com
关键词:
动态增强扫描; 扩散加权成像; 前列腺良恶性疾病
Keywords:
Dynamic enhanced-contrast MRI;  Diffusion weighted imaging;  Benign and malignant prostate disease
分类号:
R445.2;R737.25
DOI:
-
摘要:
目的探讨使用动态增强扫描（DCE-MRI） 及扩散加权成像（DWI） 对前列腺良恶性疾病的鉴别。方 法随机选取2014 年6 月至2016 年12 月贺州市中医医院放射科确诊为前列腺增生（BPH） 的患者78例为 前列腺增生组；选取同期确诊为前列腺癌患者78例为前列腺癌组；另外选取同期来检查并确诊为健康受检者30例 为对照组。对这三组受检者使用DCE-MRI及DWI，分析其DCE-MRI SI-T 曲线，测量峰值时间（Tmax），峰 值强度（Sipeak）、强化率（R），并对比DCE-MRI参数和表观扩散系数（ADC） 值。分析联合诊断在前列腺良 恶性疾病中的应用价值。结果Tmax比较，正常组>前列腺增生组>前列腺癌组；SImax%比较，前列腺增生组和前 列腺癌组>正常组；R 比较，前列腺癌组>列腺增生组>正常组；ADC 比较，前列腺癌组<正常组<前列腺增生 组，差异有统计学意义（P<0.05）。DCE-MRI 联合DWI 诊断前列腺良恶性疾病的敏感性为92.31%、特异性为 87.18%、阳性预测值为87.80%、阴性预测值为91.89%、有效性为89.74%。结论DCE-MRI及DWI在前列腺良 恶性疾病性质的临床诊断与鉴别中具有较高的应用价值，能够有效评估前列腺疾病的生物学特性。
Abstract:
Objective To investigate the differential diagnosis of benign and malignant prostate diseases by dynamic contrast- enhanced MRI (DCE- MRI) and diffusion weighted imaging (DWI). Methods From June 2014 to December 2016, 78 patients with prostate hyperplasia (BPH), 78 patients with prostate cancer and 30 healthy cases in Department of Radiology, Hezhou Traditional Chinese Medicine Hospital were studied by DCE-MRI and DWI. SI-T curve, the peak time (Tmax), peak intensity (Sipeak) and enhancement rate (R) were measured and DCE- MRI parameters and diffusion coefficient (ADC) value were compared in these groups. The value of combined diagnosis methods in prostate benign and malignant disease was analyzed. Results Sequence of Tmax from high to low was normal group, BPH group and prostate cancer group; levels of SImax% in BPH group and prostate cancer group were higher than that in normal group; sequence of R from high to low was prostate cancer group, BPH group and normal group; sequence of ADC from high to low was prostate cancer group, normal group, BPH group (P<0.05). The sensitivity of DCE-MRI combined with DWI in diagnosing benign and malignant prostate disease was 89.74% ; the specificity was 87.18% ; the positive predictive value was 84.34% ; the negative predictive value was 89.47% ; the validity was 88.46% . ConclusionDCE- MRI and DWI have high application value in the clinical diagnosis and identification of benign and malignant prostatic diseases, and they can effectively evaluate the biological characteristics of prostate diseases.

参考文献/References:

[1] 徐瑞.动态增强MRI及扩散加权成像对前列腺良恶性疾病的诊断 价值[J].医疗装备,2015,39(16):37-38.
[2] 冷晓明,韩晓蕊,徐嬿,等.IVIM－DWI 和定量DCE－MRI 鉴别 前列腺癌和前列腺增生-灌注系数的相关性研究[J].影像诊断与 介入放射学,2016,25(5):390-395.
[3] 周印,赵爽,白娇,等. 常规磁共振影像特征对前列腺外周带良恶 性病变的鉴别诊断价值探讨[J].四川大学学报(医学版),2013,44 (1):94-98.
[4] 程悦,季倩,张怡,等. 磁共振动态增强定量分析对前列腺疾病的 诊断价值[J].中华老年医学杂志,2014,33(1):55-58.
[5] 景国东,汪剑,陈录广,等.3.0T 动态增强MRI在前列腺癌诊断中 的价值[J].放射学实践,2014,29(5):482-486.
[6] 王君鑫,赵文露,杨毅,等.动态增强MRI 三维定量参数直方图诊 断前列腺癌的价值[J].中华放射学杂志,2016,50(8):609-614.
[7] 田正茂,詹先进,赵世胜,等.MRI动态增强结合DWI在前列腺良 恶性疾病中的诊断价值研究[J]. 四川医学,2016,37(12):1396- 1399.
[8] 邱铁峰,童雪明,黄勇,等. 磁共振弥散加权成像和动态增强诊断 前列腺疾病临床价值分析[J]. 医学影像学杂志,2014,24(6): 1001-1004.
[9] 周雁玲,郑国良,陈其锋,等.磁共振DWI及动态增强扫描在前列 腺疾病诊断中的价值[J]. 医学影像学杂志,2012,22(8):1363- 1366,1373.
[10] 史春雷,梅婷婷,李晓辉,等. 磁共振弥散加权成像及动态增强联 合应用对前列腺癌的诊断价值分析[J].医学影像学杂志,2014,24 (8):1455-1457.

备注/Memo

备注/Memo:
基金编号：广西壮族自治区卫生厅科研课题（Z2014348）
作者简介：陈桂娥，本科，副主任医师，研究方向：磁共振功能成像
通信作者：陈桂娥，E-mail：lilian1608@163.com
更新日期/Last Update: 2017-08-18