|本期目录/Table of Contents|

[1]余权标,谢锋,刘铁柱,等.血清Ｂ型脑钠肽肌钙蛋白联合检测对慢性阻塞性肺疾病急性加重期的临床诊断价值[J].慢性病学杂志,2017,(03):263-265.
　YU Quan-biao,XIE Feng,LIU Tie-zhu,et al.Application value of serum BNP and cTnI joint detection in patients with chronic obstructive pulmonary disease patients with acute exacerbation[J].,2017,(03):263-265.
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血清Ｂ型脑钠肽肌钙蛋白联合检测对慢性阻塞性肺疾病急性加重期的临床诊断价值(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2017年03期
页码:
263-265
栏目:
论著
出版日期:
2017-04-17

文章信息/Info

Title:
Application value of serum BNP and cTnI joint detection in patients with chronic obstructive pulmonary disease patients with acute exacerbation
作者:
余权标; 谢锋; 刘铁柱; 贺雪峰; 钟伟兰
中山市东升医院内科，广东中山528414
Author(s):
YU Quan-biao;  XIE Feng;  LIU Tie-zhu;  HE Xue-feng;  ZHONG Wei-lan
Zhongshan Dongsheng Hospital, Zhongshan, Guangdong 528414, China Corresponding author: YU Quan-biao, E-mail: kjk799@163.com
关键词:
慢性阻塞性肺病; 急性加重期; Ｂ型脑钠肽; 肌钙蛋白
Keywords:
Chronic obstructive pulmonary disease;  Acute exacerbation;  B- type natriuretic titanium;  Tropnin I
分类号:
R541.6
DOI:
-
摘要:
目的探讨联合检测慢性阻塞性肺疾病急性加重期（AECOPD） 患者的血清Ｂ型脑钠肽（BNP）、肌钙 蛋白（cTnI） 水平的临床价值。方法通过选取中山市东升医院收治AECOPD 患者及COPD 稳定期患者各30 例进行回顾性分析，分别测定血清BNP 及cTnI的水平变化，并分析两者的相关性和其与动脉血气分析及肺功能 检测相关指标之间的联系。结果AECOPD 患者血清BNP、cTnI水平明显高于COPD 稳定组（P <0.05），且 血清BNP、cTnI水平随着AECOPD 病情加重而提高（P <0.05），单独检测BNP 对AECOPD 患者诊断的敏感性 和特异性为53.33%和86.67%；而单独检测cTnI 对AECOPD 患者诊断的敏感性和特异性为76.67%和70.00%。 联合检测BNP、cTnI 对AECOPD 诊断的敏感性和特异性为70.00%和83.33%。结论血清中BNP、cTnI 均 能一定程度反映AECOPD 患者病情程度，具有较好的诊断价值。
Abstract:
Objective To explore the application value of B-type natriuretic titanium (BNP) and of Serum tropnin I (cTnI) in diagnosis of chronic obstructive pulmonary disease patients with acute exacerbation (AECOPD). Methods Thirty patients with AECOPD and thirty patients with stable COPD were selected into research to measure the serum level of BNP and cTnI. Result Compared with the stable COPD group, levels of BNP and cTnI in the AECOPD group increased significantly (P<0.05), and the levels increased following the aggravation of the disease. The sensitivity and specificity of BNP were 53.33% and 86.67% for AECOPD, while those of cTnI were 76.67% and 70.00%, and those of joint detection were 70.00% and 83.33%. Conclusion The serum levels of BNP and cTnI have high clinical application value for AECOPD patients.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介：余权标，本科，主治医师，主要从事普通内科 方向工作 通信作者：余权标，E-mail：kjk799@163.com
更新日期/Last Update: 2017-03-18