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[1]许英,杨敏,关奉菊,等.初诊2 型糖尿病患者胰岛素泵强化治疗的效果观察[J].慢性病学杂志,2017,(02):135-137.
 XU Ying,YANG Min,GUAN Feng-ju,et al.Effect of insulin pump therapy on newly diagnosed patients with type 2 diabetes[J].,2017,(02):135-137.
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初诊2 型糖尿病患者胰岛素泵强化治疗的效果观察(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2017年02期
页码:
135-137
栏目:
论著
出版日期:
2017-03-27

文章信息/Info

Title:
Effect of insulin pump therapy on newly diagnosed patients with type 2 diabetes
作者:
许英杨敏关奉菊王立杰郎青春
通辽市医院内分泌科,内蒙古通辽028000
Author(s):
XU Ying YANG Min GUAN Feng-ju WANG Li-jie LANG Qing-chun
Department of Endocrinology, Tongliao Hospital, Tongliao, NeiMongol, 028000, China Corresponding author:XU Ying,E-mail: tlxuying@126.com
关键词:
2型糖尿病初诊胰岛素泵
Keywords:
Type 2 diabetes mellitus Newly diagnosed Insulin pump therapy
分类号:
R587.1
DOI:
-
摘要:
目的探讨胰岛素泵即胰岛素皮下持续输注(CSII) 治疗初诊2 型糖尿病患者的临床疗效。方法选 取通辽市医院2014 年8 月—2015 年8 月收治的初诊2 型糖尿病住院患者200 例,采用随机数字表法分为观察组和 对照组,每组100例。其中观察组行CSII治疗,对照组行多次皮下注射胰岛素(MSII) 治疗;均治疗2周。比较 两组治疗前后空腹血糖(FPG)、餐后2 h 血糖(2hPG)、糖化血红蛋白(HbA1c)、胰岛素抵抗指数(Homa- IR) 和胰岛素β细胞指数(Homa-β)。结果两组治疗后FPG 和2hPG 均较治疗前下降,以观察组为著(P 均 <0.05);两组Homa-IR 较治疗前下降,Homa-β 较治疗前升高,差异有统计学意义(P 均<0.05),两组之间的 比较,P 均>0.05;两组HbA1c值比较,P>0.05。结论CSII可修复初诊2型糖尿病患者的胰岛β细胞功能,促 进血糖水平达标。
Abstract:
Objective To investigate the effect of insulin pump therapy namely continuous subcutaneous insulin infusion (CSII) on newly diagnosed patients with type 2 diabets. Methods A total of 200 patients were recruited from Tongliao hospital from August 2014 to August 2015, 100 on CSII, 100 on multiple-subcutaneous insulin injections(MSII),and all treated for two weeks. Fasting blood glucose (FPG), 2h postprandial blood glucose(2hPG), glycosylated hemoglobin(HbA1c),Homa-IR and Homa-β were compared between the CSII group and the MSII group. Results FPG, 2hPG in two groups, espetially the CSII group were lower after treatment than befrore treatment (all P<0.05). Homa-IR was decreased, Homa-β was increased in the two groups. There were no difference of Homa-IR, Homa- β, HbA1c between the CSII and the MSII group (all P>0.05). Conclusion CSII can help to restore the function of islet beta cells and the glucose levels return to normal in newly diagnosed patients with type 2 diabetes.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介:许英,大学本科,主任医师,研究方向: 慢性病诊断与防治 通信作者:许英,E-mail:tlxuying@126.com
更新日期/Last Update: 2017-02-18