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[1]许云俊.左卡尼汀注射液治疗老年冠心病心力衰竭的临床疗效[J].慢性病学杂志,2016,(09):976-978.
　XU Yun-jun.Clinical effect of levocarnitine injection on treatment of elderly patients with coronary heart disease and heart failure[J].,2016,(09):976-978.
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左卡尼汀注射液治疗老年冠心病心力衰竭的临床疗效(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2016年09期
页码:
976-978
栏目:
论著
出版日期:
2016-10-27

文章信息/Info

Title:
Clinical effect of levocarnitine injection on treatment of elderly patients with coronary heart disease and heart failure
作者:
许云俊
衡阳市中心医院心血管中心，湖南衡阳421001
Author(s):
XU Yun-jun
Cardiovascular Center, Central Hospital of Hengyang, Hengyang, Hunan 421001,China Corresponding author: XU Yun-jun, E-mail: 1137129631@qq.com
关键词:
老年冠心病; 左卡尼汀注射液; 心力衰竭; 临床疗效
Keywords:
Coronary heart disease;  Levocarnitine injection;  Heart failure;  Clinical effect
分类号:
R541.4
DOI:
-
摘要:
目的分析研讨左卡尼汀注射液治疗老年冠心病心力衰竭（简称“ 心衰”） 的临床疗效。方法 选取68 例2014 年7 月—2015 年12 月衡阳市中心医院收治的老年冠心病心衰患者，随机分为对照组和观察 组，各34 例，对照组接受常规治疗（硝酸脂类药物、利尿剂、血管紧张素转换酶抑制剂及β 受体阻滞剂 等）， 观察组在对照组治疗基础上加用左卡尼汀注射液。将两组患者的临床疗效、左室舒张末期容积 （LVEDD）、左室收缩末期容积（LVESD）、左室射血分数（EF）、心输血量（CO） 等心功能指标及空腹 血糖(FPG)、餐后血糖(PPG)、糖化血红蛋白（HbA1c） 水平进行对比分析。结果经治疗后， 观察组 （94.12%） 总有效率明显高于对照组（79.14%）， 差异有统计学意义（P<0.05）； 观察组患者的LVEDD、 LVESD、EF、CO 等心功能指标改善情况明显优于对照组，差异有统计学意义（P<0.05）；观察组FPG、 PPG、HbA1c 水平均明显优于对照组，差异有统计学意义（P<0.05）。结论左卡尼汀注射液治疗老年冠 心病心力衰竭，其疗效确切，可明显改善患者的心功能，值得临床应用并推广。
Abstract:
Objective To investigate the clinical effect of levocarnitine injection on treatment of elderly patients with coronary heart disease and heart failure. Methods A total of 68 elderly patients with coronary heart disease and heart failure in Central Hospital of Hengyang from July, 2014 to December, 2015 were selected and randomly divided into the control group and the study group. Patients in the control group were given the routine treatment including nitrates drugs, diuretics and β- blocker, etc., while patients in the study group were treated with the levocarnitine injection on the base of the routine treatment. Then, the left ventricular end diastolic volume (LVEDD), left ventricular end systolic volume (LVESD), left ventricular ejection fraction (EF), cardiac output (CO), fasting plasma glucose(FPG), postprandial plasma glucose (PPG), HbA1c levels were compared between the two groups. Results After treatment, the total effective rate in the study group was 94.12% , which was significantly higher than that in the control group (79.14%, P<0.05). LVEDD, LVESD, EF, CO in the study group were significantly better than those in the control group (all P<0.05). The levels of FPG, PPG, HbA1c in the study group were significantly better than those in the control group (all P<0.05). Conclusion Levocarnitine injection is effective for the treatment of elderly patients with coronary heart disease and heart failure, and it can significantly improve the patient's heart function, thus it is worthy to be applied and promoted in the clinic.

参考文献/References:

[1] 吴福霞. 左卡尼汀在冠心病中的临床效果研究[J]. 现代诊断与 治疗,2013,1(15):3457-3458.
[2] 王辉.116 例老年冠心病心力衰竭的治疗[J]. 中外医疗,2013,33 (33):42-43.
[3] 刘卫强. 左卡尼汀注射液治疗老年冠心病心力衰竭的临床疗效 分析[J]. 右江医学,2014,42(2):189-191.
[4] 李天荣,陆洁. 左卡尼汀注射液治疗老年冠心病心力衰竭的临 床疗效观察[J]. 中国医药指南,2014,(31):214-215.
[5] 丁健,冯清胜. 左卡尼汀注射液治疗老年冠心病心力衰竭的效 果评价[J]. 中国疗养医学,2015,(7):728-729.
[6] 梁淑香,刘茂月. 左卡尼汀注射液治疗冠心病128 例疗效观察[J]. 中国医药指南,2013,(3):82-83.
[7] 李振军,张学山,周丽梅,等. 左卡尼汀注射液辅助治疗老年冠 心病心力衰竭78 例疗效观察[J]. 齐齐哈尔医学院学报,2015, (12):1780-1782.
[8] 李成秋. 左卡尼汀注射液治疗老年冠心病心衰的临床疗效[J]. 中国实用医药,2016,11(4):109-110.

备注/Memo

备注/Memo:
作者简介：许云俊，硕士，主治医师，研究方向：心律失常，心衰，冠心病介入治疗 通信作者：许云俊，E-mail: 1137129631@qq.com
更新日期/Last Update: 2016-10-27