|本期目录/Table of Contents|

[1]张卫权,梁转合,黎武军,等.血清LDL-C/HDL-C 比值与原发性高血压分级的相关性分析[J].慢性病学杂志,2016,(09):956-958.
　ZHANG Wei-quan*,LIANG Zhuan-he,LI Wu-jun,et al.Correlation analysis of essential hypertension grade and the ratio of serum LDL-C/HDL-C[J].,2016,(09):956-958.
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血清LDL-C/HDL-C 比值与原发性高血压分级的相关性分析(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2016年09期
页码:
956-958
栏目:
论著
出版日期:
2016-10-27

文章信息/Info

Title:
Correlation analysis of essential hypertension grade and the ratio of serum LDL-C/HDL-C
作者:
张卫权1;  梁转合2;  黎武军1;  郑志1;  梁瑞川1;  张惠芬1
1. 江门市新会区双水镇中心卫生院内科，广东江门529153； 2. 江门市新会区人民医院心内科，广东江门529100
Author(s):
ZHANG Wei-quan*;  LIANG Zhuan-he;  LI Wu-jun;  ZHENG Zhi;  LIANG Rui-chuan;  ZHANG Hui-fen
*Department of Internal Medicine, Health Centre of Shuangshui Town in Xinhui District, Jiangmen, Guangdong 529153, China
关键词:
低密度脂蛋白胆固醇; 高密度脂蛋白胆固醇; 高血压
Keywords:
Low density lipoprotein cholesterol;  High density lipoprotein cholesterol;  Essential hypertension
分类号:
R544.1
DOI:
-
摘要:
目的探讨血清低密度脂蛋白胆固醇（LDL-C） 与高密度脂蛋白胆固醇（HDL-C） 比值与原发性高血 压（以下简称高血压） 分级的关系。方法随机抽取新诊断的高血压患者150 例，分为1 级、2 级、3 级高血压 组，每组50 例，另取50 例血压正常者作为对照组，分别测定每组对象的血压、体质量、身高、血清甘油三脂 （TG）、总胆固醇（TC）、LDL-C、HDL-C 水平，计算LDL-C/HDL-C 比值，并进行组间比较。各项血脂指 标与血压水平及高血压分级的相关性采用Pearson相关分析。结果四组对象的血脂指标比较差异有统计学意义 （P＜0.05）；Pearson 相关分析显示，TG、TC、LDL-C 水平、LDL-C/HDL-C 比值分别与收缩压、舒张压、 高血压分级呈正相关，HDL- C 水平分别与收缩压、舒张压、高血压分级呈负相关，均P＜0.05。LDL- C/ HDL-C 比值与高血压分级的相关系数的绝对值更接近1，相关性更强。结论血清LDL-C/HDL-C 比值与原 发性高血压分级的相关性较单项血脂指标更强。
Abstract:
Objective To investigate the relationship between essential hypertension grade and the ratio of serum low density lipoprotein cholesterol (LDL-C) to high density lipoprotein cholesterol (HDL-C). Methods A total of 150 newly confirmed hyperpietic were randomly selected and divided into level 1, level 2, level 3 group, 50 cases in each group. Totally 50 individuals without hypertension were selected as the control group. Blood pressure, body mass index (BMI), serum triglyceride (TG), total cholesterol (TC), LDL- C, HDL- C, LDL- C/HDL- C of four groups were measured and compared. The relationship between above indexes and essential hypertension grade were analyzed by Pearson correlation analysis method. Results The levels of TG, TC, LDL- C and HDL- C between the four groups were significantly different (P＜0.05). TG, TC, LDL-C and LDL-C/HDL-C were positively correlated with essential hypertension grade, systolic blood pressure (SBP) and diastolic blood pressure (DBP); HDL- C was negatively correlated with essential hypertension grade, SBP and DBP (all P＜0.05). The absolute value of correlation coefficient between LDL- C/HDL- C and essential hypertension grade was more close to 1, so the correlation was stronger. Conclusions The correlation between LDL-C/HDL-C and essential hypertension grade is stronger than other single lipid indexes.

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备注/Memo

备注/Memo:
基金项目：江门市科技计划项目（20150020000829） 作者简介：张卫权，本科，副主任医师，研究方向：内科 通信作者：张卫权，E-mail: zhwq111@126.com
更新日期/Last Update: 2016-10-27