|本期目录/Table of Contents|

[1]王斌,陈珮,颜雪芸,等.原发性高血压患者心踝指数及相关危险因素研究[J].慢性病学杂志,2016,(06):598-601.
　WANG Bin,CHEN Pei,YAN Xue-yun,et al.Study on cardio-ankle vascular index and related risk factors in patients with essential hypertension[J].,2016,(06):598-601.
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原发性高血压患者心踝指数及相关危险因素研究(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2016年06期
页码:
598-601
栏目:
论著
出版日期:
2016-08-10

文章信息/Info

Title:
Study on cardio-ankle vascular index and related risk factors in patients with essential hypertension
作者:
王斌; 陈珮; 颜雪芸; 徐佩尔; 严丽艳; 宋琴; 秦光耀; 董艳梅
上海市闸北区市北医院心内科，上海200435
Author(s):
WANG Bin;  CHEN Pei;  YAN Xue-yun;  XU Pei-er;  YAN Li-yan;  SONG Qin;  QIN Guang-yao;  DONG Yan-mei
Cardiovascular Department, Shibei Hospital of Zhabei District in Shanghai, Shanghai 200435, China Corresponding author: CHEN Pei, E-mail: chenpei1126@163.com
关键词:
高血压; 心踝指数; 低密度脂蛋白胆固醇; 颈围; 动脉硬化
Keywords:
Hypertension;  Cardio-ankle vascular index;  Low density lipoprotein cholesterol;  Neck circumference;  Arteriosclerosis
分类号:
R541.3
DOI:
-
摘要:
目的探讨原发性高血压患者中心踝指数（CAVI） 异常比例及与并存的心血管病危险因素的相关性。方 法连续入选原发性高血压患者294 例，分别测定血压、CAVI、颈围（NC）、腰围（WC）、体质量、血脂、空 腹血糖（FPG）、同型半胱氨酸（HCY）、尿微量蛋白（UMA）、肾小球滤过率（eGFR）。采用SAS9.2 统计软件 对CAVI 异常与并存的心血管危险因素进行相关性分析。用多元线性回归（Stepwise） 对CAVI 异常的独立危险 因素进行分析。结果CAVI 异常与年龄、收缩压（SBP）、NC、体质量指数（BMI）、低密度脂蛋白胆固醇 （LDL-C） 明显相关（P <0. 01）；与WC、FPG、eGFR、UMA、HCY 无明显相关性（ P >0.05）。多元线性 回归分析：年龄、SBP、NC、LDL-C、BMI、男性分别是CAVI 异常的独立危险因素（P <0.05）。结论原发 性高血压患者中，CAVI异常与多重危险因素并存，CAVI异常与年龄、SBP、NC、LDL-C、BMI等明显相关。
Abstract:
Objective To investigate the relationship between the abnormal proportion of cardio- ankle vascular index (CAVI) and the risk factors of cardiovascular disease in patients with essential hypertension. Methods A total of 294 cases with essential hypertension were continuously selected, and blood pressure, CAVI, neck circumference (NC), waist circumference (WC), weight, blood lipids, fasting plasma glucose (FPG), homocysteine (Hcy), urinary micro albumin (UMA) and glomerular filtration rate (eGFR) were measured. These indexes were used to make correlation analysis of abnormal CAVI and coexisting cardiovascular risk factors with SAS9.2 statistical software. The independent risk factors of abnormal CAVI were analyzed by using multiple linear regression (Stepwise). Results Abnormal CAVI was significantly correlated with age, systolic blood pressure (SBP), NC, body mass index (BMI) and low density lipoprotein cholesterol (LDL- C), P <0.0001. There was no significant correlation between abnormal CAVI and WC, FPG, eGFR, UMA, Hcy ( P >0.05). Multiple linear regression analysis showed that age, SBP, NC, LDL-C, BMI and male were independent risk factors for abnormal CAVI ( P <0.05). Conclusion In patients with essential hypertension, abnormal CAVI is significantly associated with multiple risk factors such as age, SBP, NC, LDL-C, BMI.

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备注/Memo

备注/Memo:
基金项目：上海市闸北区科委课题[ZBZDI02(2009)] 作者简介：王斌，本科，主任医师，研究方向：高血压与 动脉硬化的防治 通信作者：陈珮，E-mail: chenpei1126@163.com
更新日期/Last Update: 2016-08-27