|本期目录/Table of Contents|

[1]何剑养,邓学灵,李党坚,等.纤维支气管镜肺泡灌洗治疗儿童肺炎重症支原体的临床观察[J].慢性病学杂志,2016,(05):505-507.
　HE Jian-yang,DENG Xue-ling,HE Cai-yun,et al.Clinical effect of bronchoalveolar lavage on patients with severe mycoplasma[J].,2016,(05):505-507.
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纤维支气管镜肺泡灌洗治疗儿童肺炎重症支原体的临床观察(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2016年05期
页码:
505-507
栏目:
论著
出版日期:
2016-07-26

文章信息/Info

Title:
Clinical effect of bronchoalveolar lavage on patients with severe mycoplasma
作者:
何剑养; 邓学灵; 李党坚; 何彩云; 林小霞
广东省怀集县人民医院,广东怀集526400
Author(s):
HE Jian-yang;  DENG Xue-ling;  HE Cai-yun;  LIN Xiao-xia
People's Hospital of Huaiji County in Guangdong Province, Huaiji, Guangdong 526400, China Corresponding author: HE Jian-yang, E-mail: hejianyang0304@163.com
关键词:
重症肺炎支原体肺炎; 纤维支气管镜; 支气管肺泡灌洗; 儿童
Keywords:
Severe mycoplasma pneumonia;  Bronchoscopy;  Bronchoalveolar lavage;  Children
分类号:
R725.6
DOI:
-
摘要:
目的探讨纤维支气管镜支气管肺泡灌洗（纤支镜肺泡灌洗）在重症肺炎支原体肺炎（SMPP）中的应用 效果，并比较治疗时机对治疗效果的影响。方法55 例SMPP 患儿随机分为治疗组（27 例）及对照组（28 例）， 对照组给予大环内酯类抗生素抗感染、静脉滴注甲基泼尼松龙、雾化吸入布地奈德及其他对症治疗，治疗组在 对照组的基础上，分别于患儿的体温稳定期（Ⅰ组）或急性发热期（Ⅱ组）加用纤支镜肺泡灌洗。疗程均为7 d。 7 d 后观察临床疗效，记录退热时间、咳嗽明显改善时间、肺部啰音消失时间和住院时间；1 个月后门诊随访， 统计肺部炎症吸收率。结果治疗组和对照组总有效率分别为89.29% 和66.67% ，差异有统计学意义（χ2= 6.446，P<0.05）。治疗组退热时间、咳嗽明显改善时间、肺部啰音消失时间、住院时间明显短于对照组，差异有 统计学意义（P 均<0.05），治疗组1 个月后肺部炎症吸收率明显高于对照组。Ⅱ组咳嗽明显改善时间、肺部啰 音消失时间、住院时间明显短于Ⅰ组，差异有统计学意义（P 均<0.05）；两组退热时间、1 个月后肺部炎症吸收 率比较，P 均>0.05。结论纤支镜肺泡灌洗能提高SMPP 的疗效，且在急性发热期应用效果更好。
Abstract:
Objective To observe the efficacy of bronchoalveolar lavage on patients with severe mycoplasma pneumonia (SMPP), and investigate the influence of treatment option on the therapeutic effect. Methods Fifty- five cases of infantile patients with SMPP were divided into treatment group (n=27) and control group (n=28). Control group received macrolide antibiotics, methylprednisolone by intravenous drop, budesonide aerosol inhalation and other symptomatic treatment for seven days. Treatment group received bronchoalvellar lavage in the stabilization period ( Ⅰ group) or the stage of fervescence (Ⅱ group) for seven days on the basis of treatment in control group. After seven days, clinical effects were observed, meanwhile fever clearance time, disappearance time of cough and pulmonary rales and the length of hospital stay were recorded. After one month, the pulmonary inflammatory absorption rate in outpatients follow-up was counted. Results Total effective rate in treatment group and control group was 89.29% and 66.67%, respectively, and there was statistical difference between them (χ2=6.446, P< 0.05). Compared with control group, fever clearance time, disappearance time of cough and pulmonary rales, the length of hospital stay in treatment group were shorter, and the rate of pulmonary inflammatory absorption in treatment group was higher (all P<0.05). Disappearance time of cough and pulmonary rales, the length of stay were shorter in Ⅱ group than those in Ⅰ group, and there were significant differences (all P<0.05), but the fever clearance time, pulmonary inflammation absorption weren’t different between the two groups (all P>0.05). Conclusions Bronchoscopy lavage can help to improvethe curative effect in patients with SMPP, and it can get the better application effect in the stage of fervescence.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介：何剑养，本科，副主任医师，主要研究方向为儿科疾病的诊治 通信作者：何剑养，E-mail:hejianyang0304@163.com
更新日期/Last Update: 2016-07-27