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Title:: Efficacy of Chinese medicine comprehensive treatment program for moderate to severe mood disorders menopausal patients

Author(s):: YIN Hao; Zaozhuang Shanting North Town Center Hospital, Zaozhuang, Shandong 277218, China Corresponding author: YIN Hao, E-mail: kairuitg@163.com

摘要:: 目的探讨中医综合治疗方案对绝经期中重度情绪障碍患者的疗效。方法选取120 例绝经期中重度情绪障碍患者，随机分为观察组和对照组，各60 例。对照组采用疏肝养心方，每日1 剂，煎两次混合后分早晚服用。观察组在对照组治疗的基础上采用安神法针灸，穴取百会、气海、神庭、关元、中极、双侧合谷、神门、太冲和内关穴，每7 d 为1 疗程，连续治疗6 d，休息1 d。治疗前、治疗6 周后采用汉密尔顿抑郁量表（HAMD）对两组患者进行评分，并评估治疗效果。采用SPSS 18.0 统计学软件分析，计量资料用均数±标准差（ xˉ±s）表示，采用t 检验，计数资料用率（%）表示，采用χ2 检验，P＜0.05 表示差异有统计学意义。结果观察组患者治疗的总有效率为90.00%，对照组的为73.33%，两组间差异有统计学意义（P<0.05）。结论中医综合治疗方案能够有效改善绝经期中重度情绪障碍患者的负性情绪，具有临床推广意义。

Abstract:: Objective To explore the effect of Chinese medicine comprehensive program in treating patient with moderate to severe menopausal mood disorder. Methods A total of 120 patients of moderate to severe menopausal mood disorders were randomly divided into the observation group and control group. The control group adopted Shugan Yang Xin Fang. The drug was taken twice every one day during morning and evening, after being stewed twice and mixed eventually. The observation group received tranquilization acupuncture treatment on top of the same treatment that the control group received. The acupuncture points included Baihui, Air Sea, God Court, Guan Yuan, Chinese Pole, Bilateral Gu, God Door, Taichong and Neiguan. Each course included 7 d, with 6d continuous treatment and 1d rest. The Hamilton Depression Scale (HAMD) score was evaluated for the two groups of patients before treatment and at 6 weeks of treatment, and the therapeutic effect was evaluate. The statistics software SPSS18.0 was used for data analysis. Results The total effective rate in the observation group was 90.00% while that in the control group was 73.33%. There was a statistically significant difference between the two groups (P<0.05). Conclusions Chinese medicine comprehensive treatment program can improve the negative emotion of menopausal patients with moderate to severe mood disorder.