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《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:

期数:

2015年05期

页码:

497-500

栏目:

论著

出版日期:

2015-10-15

文章信息/Info

Title:

Evaluation of validity and reliability on arthritis Patient-Reported Outcomes scale

作者:

李鹭; 白文瑾; 张岩波

山西医科大学公共卫生学院，太原 030001

Author(s):

LILu; BAIWen-jin; ZHANG Yan-bo

DepartmentofHealth Statistics, School ofPublicHealth,ShanxiMedicalUniversity,Taiyuan,shanxi03001China. Correspondingauthor:ZHANG Yan-bo,E-mail:sxmuzyb@126.com

关键词:

关节炎; 患者报告结局; 信度; 效度

Keywords:

Arthritis;  Patient-Reported Outcomes (PRO);  Reliability;  Validity

分类号:

R195.4

DOI:

-

摘要:

目的 评价自行编制的关节炎患者报告临床结局（PRO）量表的信度、效度和可接受性。方法 采用 关节炎PRO量表对山西医科大学第一医院、第二医院及太原市化二建集团社区医院471例患者进行自评式 调查，运用克朗巴赫系数法、验证性因子分析法、t检验等方法评价量表的信度、效度和反应度。结果 本 量表各领域的克朗巴赫α系数分别为：生理功能（PHF）0.904、心理功能（PSF）0.808、社会功能 （SOF）0.648、治疗感受（TRE）0.754，整个量表为0.884。结构效度方面，除PHF领域比较拟合指数 （CFI）为0.860外，其他各个领域的CFI均大于0.90，整体模型拟合好。在反应度方面，除了在PHF领域 的皮肤表面症状和精力方面，PSF领域的自信心方面，SOF领域的社会支持和社会活动方面以及SOF领 域，观察对象在治疗前后差别没有统计学意义（P均>0.05）外，其余方面差异均有统计学意义（P均＜ 0.05）。调查表的回收率和有效率均较高，表明该量表有好的可接受性。结论 关节炎PRO量表具有较好 的信度、效度、反应度和可接受性，量表可作为关节炎新药和器械临床试验疗效评价的终点指标。

Abstract:

Objective To evaluate the reliability, validity and acceptability of the arthritis patient-reported outcomes(PRO) scale. Methods471 arthritis patients were participated in the investigation of two large hospitals and one community hospital located in Taiyuan. By adopting Cronbach coefficient, confirmatory factor analysis, and t-test, the reliability, validity and feasibility of the scale were evaluated.Results The Cronbach'sα coefficient about the scale was 0.884, the physiology function domain was 0.904, the psychology function domain was 0.808, the social function domain was 0.648 and the treatment experi-ence function was 0.754. About contract validity, except for CFI of physiological function field was 0.860, CFI of other fields were larger than 0.90, whole model fitting was good. About responsibility, in addition to skin surface symptoms and energy of physiology function domain, self-confidence of psy-chology function domain, social relations and social activities of social function domain and social func-tion domain, observation object didn’t have statistical significance before and after therapy, other aspects were statistically significance. The recovery rate and the efficient rate of the questionnaire were good which indicate that the scale had a high clinical feasibility.Conclusions The arthritis PRO scale has good reliability, validity, responsibility and acceptability. Scale can be used as the endpoints of curative effect evaluation of arthritis clinical new drug and instrument trial.

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备注/Memo

备注/Memo:

基金项目：国家自然科学基金资助项目（81273180） 作者简介：李鹭，在读硕士，主要从事潜变量研究工作 通信作者：张岩波，E-mail：sxmuzyb＠126.com

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更新日期/Last Update: 2015-10-16