|本期目录/Table of Contents|

[1]石江顺,赵施竹.急性冠状动脉综合征患者尿免疫球蛋白Ｍ水平及意义[J].慢性病学杂志,2013,(12):945-947.
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急性冠状动脉综合征患者尿免疫球蛋白Ｍ水平及意义(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2013年12期
页码:
945-947
栏目:
专题报道
出版日期:
2013-12-30

文章信息/Info

Title:
-
作者:
石江顺; 赵施竹
河南鹤壁煤业公司总医院,河南 鹤壁 458000
Author(s):
-
关键词:
急性冠状动脉综合征;  尿免疫球蛋白M;  微量白蛋白尿;  胸痛;  心血管事件
Keywords:
-
分类号:
R541.4
DOI:
-
摘要:
目的 检测急性冠状动脉综合征(ACS)患者尿免疫球蛋白M(IgM)水平,并探讨其与ACS患者心血管结局的关系。方法 选取因急性胸痛怀疑ACS在河南鹤壁煤业公司总医院急诊科就诊的患者180例,收集包括病史、体格检查、12导联心电图(ECG)、心肌钙蛋白T(TnT)等临床资料,并检测尿白蛋白、IgM/肌酐比值等。结果 确诊ACS 50例(男性28例),稳定性心绞痛(SA)62例(男性38例),非特异胸痛(NS)68例(男性36例)。与NS相比,ACS患者尿白蛋白和尿IgM排泄高(P均<0.05); SA和NS患者之间比较差异无统计学意义(P均>0.05)。随访2年,蛋白尿和IgM尿越严重,心血管患者死亡率就越大(95% CI:1.48～5.66,P=0.002); Kaplan Meier曲线分析显示,MA(≥3 mg/mmol)和高水平尿IgM(≥0.005 4 mg/mmol)患者较无MA和低IgM尿患者发生新的心血管事件危险增加3倍(RR=3.3,95% CI: 1.1～9.9,P=0.001)。结论 胸痛为主诉到达急诊科就诊而被怀疑有ACS的患者较非特异性胸痛患者存在较高水平的MA和尿IgM,且IgM尿与其发生重要心血管事件高危险性有关。
Abstract:
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参考文献/References:

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备注/Memo

备注/Memo:
作者简介:石江顺,本科,副主任医师,主要从事急诊内科临床诊疗工作 通讯作者:石江顺,E-mail:348623136@qq.com
更新日期/Last Update: 2013-12-30