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[1]李霞,杨兆文,王威严,等.莱姆病４０例病例资料分析[J].慢性病学杂志,2013,(09):671-674.
　LI Xia,YANG Zhao-wen,WANG Wei-yan,et al.Analysis of 40 cases of Lyme disease[J].,2013,(09):671-674.
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莱姆病４０例病例资料分析(PDF)

《慢性病学杂志》[ISSN:1674-8166/CN:11-5900/R]

卷:
期数:
2013年09期
页码:
671-674
栏目:
论著
出版日期:
2013-09-30

文章信息/Info

Title:
Analysis of 40 cases of Lyme disease
作者:
李霞; 杨兆文; 王威严; 户中丹; 张源潮
山东大学附属省立医院风湿免疫科,山东 济南 250021
Author(s):
LI Xia;  YANG Zhao-wen; WANG Wei-yan; HU Zhong-dan; ZHANG Yuan-chao
Department of Rheumatology and Immunology, Provincial Hospital Affiliated to Shandong University,Jinan,Shandong 250021,China Corresponding author:ZHANG Yuan-chao,E-mail:qryang720@163.com
关键词:
莱姆病;  病例分析;  诊断;  治疗
Keywords:
Lyme disease;  Case analysis;  Diagnosis;  Treatment
分类号:
R514
DOI:
-
摘要:
目的 通过对40例莱姆病住院病例进行分析,探讨山东地区莱姆病临床特征、实验室检查特点、诊断以及治疗方法。方法 搜集山东大学附属省立医院2010年8月至2013年3月收治的40例莱姆病住院患者,对其临床资料进行分析归纳,比较莱姆病患者的临床表现及实验室检查特点、诊断、综合治疗及预后。结果 男性患者7例,年龄的中位数43.86岁,女性患者33例,年龄的中位数34.27岁,男女发病年龄无统计学差异; 患者职业以农民为主,共15例,占37.5%; 患者血沉(ESR)增快占65.0%,C反应蛋白(CRP)增高占57.5%; 男性患者血沉(38.14±32.411)mm/h,女性患者血沉(43.48±30.960)mm/h,采用两独立样本t检验,P=0.68; 男性患者CRP(58.81±68.950)mg/L,女性患者CRP(31.73±46.30)mg/L,采用两独立样本t检验,P=0.35; 合并风湿病组ESR(51.64±35.465)mm/h,未合并风湿病组ESR(37.65±27.574)mm/h,采用两独立样本t检验,P=0.18。合并风湿病组CRP(60.66±66.899)mg/L,未合并风湿病组CRP(23.45±34.981)mg/L,采用两独立样本Mann-Whitney U检验,P=0.009。结论 莱姆病患者任何年龄组均可发病,男女发病无明显差异,发病人群以户外工作者(尤其农民)多见,实验室检查有急性时相反应物ESR、CRP的增高。
Abstract:
Objective To study the clinical manifestations and laboratory features,diagnosis and treatment of Lyme disease. Methods Retrospectively analyze 40 inpatients with Lyme disease(LD)treated in Provincial Hospital Affiliated to Shandong University from August 2010 to March 2013 in order to compare the clinical manifestations,laboratory features,diagnosis,comprehensive treatment and prognosis. Results 40 cases were enrolled from August 2010 to March 2013,including 7 males and 33 females,age of each group showed no significant statistical difference.Occupational distribution of 40 cases indicates that outdoor workers especially farmers account for the most,which is 15 cases; As for the laboratory features,it shows that ESR of 26 cases(65.0%)elevated,CRP increased in 23 cases(57.5%); Male patients with ESR(38.14 ± 32.411)mm / h,female patients with ESR(43.48 ± 30.960)mm / h,there was no significant statistical difference(P=0.683).Male patients with CRP(58.81 ± 68.950)mg / L,female patients with CRP(31.73 ± 46.299)mg/L,there was no significant statistical difference(P=0.353).According to whether patients complicated with other autoimmune diseases(AID),they are divided into two groups.ESR of each group showed no significant statistical difference(t=1.383,P=0.175).CRP of each group showed significant statistical difference(Mann-Whitney U test,P=0.009). Conclusions This study confirms that LD patients can be found in any age group and both males and females; outdoor workers(especially farmers)are apt to get LD.Shandong province is LD endemic area.Features of laboratory check include ESR and CRP increased.

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备注/Memo

备注/Memo:
本文为“泉城之秋——陆台莱姆病研讨会暨免疫病学中国泰山论坛”征文 作者简介:李霞,博士研究生,主要从事莱姆病发病机制等方面研究 通讯作者:张源潮,E-mail:qryang720@163.com
更新日期/Last Update: 2013-09-30